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Gene Review:

SLC25A1 - solute carrier family 25 (mitochondrial...

Bos taurus

Claeys, D. et al., Evans, C.T. et al., Lüthy, R. et al., Wolffram, S. et al.

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High impact information on SLC25A1

Tricarboxylate carrier of bovine liver mitochondria. Purification and reconstitution [1].
The carrier, after reconstitution in phospholipid vesicles, catalyzed the exchange of [14C]citrate against citrate, malate, and threo-D8-isocitrate and was inhibited by the specific tricarboxylate carrier inhibitor 1,2,3-benzenetricarboxylic acid [1].
8. Furthermore, citrate transport across the intestinal brush border membrane appears to be mediated by an electroneutral process [2].
3. 50% inhibition of citrate transport was observed using palmitoyl-CoA and oleoyl-CoA at approx. 4-5 microM when the tricarboxylate carrier was saturated with L-malate as counter-anion [3].

Associations of SLC25A1 with chemical compounds

The tricarboxylate carrier of bovine liver mitochondria has been solubilized by Triton X-114 and purified by chromatography on hydroxylapatite and Silica Gel 60 [1].
The tricarboxylate carrier from beef liver mitochondria was reconstituted into liposomes using a protocol based on the absorption of Triton X-100 to hydrophobic Amberlite XAD-2 beads [4].

References

Tricarboxylate carrier of bovine liver mitochondria. Purification and reconstitution. Claeys, D., Azzi, A. J. Biol. Chem. (1989) [Pubmed]
Transport of tri- and dicarboxylic acids across the intestinal brush border membrane of calves. Wolffram, S., Bisang, B., Grenacher, B., Scharrer, E. J. Nutr. (1990) [Pubmed]
Regulation of citrate efflux from mitochondria of oleaginous and non-oleaginous yeasts by long-chain fatty acyl-CoA esters. Evans, C.T., Scragg, A.H., Ratledge, C. Eur. J. Biochem. (1983) [Pubmed]
Novel reconstitution and enzymatic assay of the mitochondrial tricarboxylate carrier. Lüthy, R., Azzi, A. Anal. Biochem. (1989) [Pubmed]

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AGOS_AGL064W	Ashbya gossypii ATCC 10895
K11H3.3	Caenorhabditis elegans
SLC25A1	Canis lupus familiaris
slc25a1a	Danio rerio
sea	Drosophila melanogaster
SLC25A1	Gallus gallus
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MGG_03479	Magnaporthe oryzae 70-15
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NCU05075	Neurospora crassa OR74A
SLC25A1	Pan troglodytes
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SPAC19G12.05	Schizosaccharomyces pombe 972h-
slc25a1	Xenopus (Silurana) tropicalis

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