Gene Review:
lmnb2 - lamin B2
Danio rerio
Synonyms:
SO:0000704, im:7142331, lamin, wu:fb94e05, wu:fb95e12, ...
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High impact information on lmnb2
- Nuclear membrane proliferation could also be induced by lamin B2 in COS-7 cells and in zebrafish embryos but not by human lamin A in COS-7 cells [1].
- Such morphological alterations were not observed with Drosophila lamin C, a lamin without this motif or with a lamin B2 mutant (B2-SxxM) where the cysteine of the CxxM motif is replaced by a serine [1].
References
- The lamin CxxM motif promotes nuclear membrane growth. Prüfert, K., Vogel, A., Krohne, G. J. Cell. Sci. (2004) [Pubmed]
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