Gene Review:
Tekt4 - tektin 4
Rattus norvegicus
Synonyms:
RGD1308075, Tek4, Tektin-4, Tektin4
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High impact information on Tekt4
- Molecular cloning of a new member of TEKTIN family, Tektin4, located to the flagella of rat spermatozoa [1].
- Reverse-transcriptional-PCR (RT-PCR) analysis indicated that Tektin4 was predominantly expressed in testis and its expression was upregulated during testis development [1].
- Tektin4 gene, which was mapped to rat chromosome 10q12, is composed of six exons and spanning 5 kb [1].
- Tektin4 protein was predominantly localized in the flagella of spermatozoa, suggesting that it might works as a flagellar component requisite for flagellar stability or sperm motility [1].
Analytical, diagnostic and therapeutic context of Tekt4
- In situ hybridization analysis showed that Tektin4 mRNA was localized in round spermatids in the seminiferous tubules of the rat testis [1].
- A new member of the TEKTIN gene family, which was designated as rat Tektin4, was obtained by PCR technique combined with yeast two-hybrid screening [1].
References
- Molecular cloning of a new member of TEKTIN family, Tektin4, located to the flagella of rat spermatozoa. Matsuyama, T., Honda, Y., Doiguchi, M., Iida, H. Mol. Reprod. Dev. (2005) [Pubmed]
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