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Gene Review

GATA4  -  GATA binding protein 4

Bos taurus

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Disease relevance of GATA4


High impact information on GATA4


Anatomical context of GATA4

  • Staining for GATA-4 was a useful method for identifying and quantifying Sertoli cell nuclei in both pre- and postpubertal bulls [2].

Associations of GATA4 with chemical compounds

  • Surprisingly, PASMC express GATA-4, and 5-HT up-regulates the GATA DNA binding activity [1].

Analytical, diagnostic and therapeutic context of GATA4


  1. Activation of GATA-4 by serotonin in pulmonary artery smooth muscle cells. Suzuki, Y.J., Day, R.M., Tan, C.C., Sandven, T.H., Liang, Q., Molkentin, J.D., Fanburg, B.L. J. Biol. Chem. (2003) [Pubmed]
  2. Testicular development of Zebu bulls after chronic treatment with a gonadotropin-releasing hormone agonist. Jiménez-Severiano, H., Mussard, M.L., Fitzpatrick, L.A., D'Occhio, M.J., Ford, J.J., Lunstra, D.D., Kinder, J.E. J. Anim. Sci. (2005) [Pubmed]
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