Gene Review:
tum - tumbleweed
Drosophila melanogaster
Synonyms:
13345, AcGAP, CG13345, DRacGAP, Dmel\CG13345, ...
- Mutations in sticky lead to defective organization of the contractile ring during cytokinesis and are enhanced by Rho and suppressed by Rac. D'Avino, P.P., Savoian, M.S., Glover, D.M. J. Cell Biol. (2004)
- Function and regulation of Tumbleweed (RacGAP50C) in neuroblast proliferation and neuronal morphogenesis. Goldstein, A.Y., Jan, Y.N., Luo, L. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Tum/RacGAP50C provides a critical link between anaphase microtubules and the assembly of the contractile ring in Drosophila melanogaster. Zavortink, M., Contreras, N., Addy, T., Bejsovec, A., Saint, R. J. Cell. Sci. (2005)
- RacGap50C negatively regulates wingless pathway activity during Drosophila embryonic development. Jones, W.M., Bejsovec, A. Genetics (2005)
- DRacGAP, a novel Drosophila gene, inhibits EGFR/Ras signalling in the developing imaginal wing disc. Sotillos, S., Campuzano, S. Development (2000)
- A RhoGEF and Rho family GTPase-activating protein complex links the contractile ring to cortical microtubules at the onset of cytokinesis. Somers, W.G., Saint, R. Dev. Cell (2003)
- Overexpression of RnRacGAP in Drosophila melanogaster deregulates cytoskeletal organisation in cellularising embryos and induces discrete imaginal phenotypes. Guichard, A., Bergeret, E., Griffin-Shea, R. Mech. Dev. (1997)
- Alternative splicing of the Drosophila melanogaster rotundRacGAP gene. Hoemann, C.D., Bergeret, E., Guichard, A., Griffin-Shea, R. Gene (1996)