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Gene Review

XCL1  -  lymphotactin

Gallus gallus

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Disease relevance of LOC395914

  • IFN-alpha (1 microg) or 10 microg of lymphotactin expressing plasmids, when given simultaneously with the pcDNA3-1E vaccine, significantly protected against body weight loss induced by E. acervulina [1].
  • In particular, covaccination with EtMIC2 plus interleukin (IL)-8, IL-16, transforming growth factor-beta4, or lymphotactin significantly decreased oocyst shedding and improved weight gains beyond those achieved by EtMIC2 alone [2].

High impact information on LOC395914


Anatomical context of LOC395914


  1. Adjuvant effects of IL-1beta, IL-2, IL-8, IL-15, IFN-alpha, IFN-gamma TGF-beta4 and lymphotactin on DNA vaccination against Eimeria acervulina. Min, W., Lillehoj, H.S., Burnside, J., Weining, K.C., Staeheli, P., Zhu, J.J. Vaccine (2001) [Pubmed]
  2. Embryo vaccination against Eimeria tenella and E. acervulina infections using recombinant proteins and cytokine adjuvants. Lillehoj, H.S., Ding, X., Dalloul, R.A., Sato, T., Yasuda, A., Lillehoj, E.P. J. Parasitol. (2005) [Pubmed]
  3. Identification of a chicken "C" chemokine related to lymphotactin. Rossi, D., Sanchez-García, J., McCormack, W.T., Bazan, J.F., Zlotnik, A. J. Leukoc. Biol. (1999) [Pubmed]
  4. Chemotactic response of lymphocytes in chicken embryos infected with Mycoplasma gallisepticum. Lam, K.M., DaMassa, A.J. J. Comp. Pathol. (2003) [Pubmed]
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