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Gene Review

CD4  -  CD4 molecule

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Disease relevance of cd4

  • Four kinds of gangliosides, namely GM1a, GD1a, GD1b and GT1b and their sulfated derivatives were examined for antiviral activities against human immunodeficiency virus type 1 and abilities to modulate CD4 antigen on the cell surface [1].

High impact information on cd4


Analytical, diagnostic and therapeutic context of cd4


  1. Inhibition of infection with human immunodeficiency virus type 1 by sulfated gangliosides. Handa, A., Hoshino, H., Nakajima, K., Adachi, M., Ikeda, K., Achiwa, K., Itoh, T., Suzuki, Y. Biochem. Biophys. Res. Commun. (1991) [Pubmed]
  2. CD4 modulation and inhibition of HIV-1 infectivity induced by monosialoganglioside GM1 in vitro. Chieco-Bianchi, L., Calabrò, M.L., Panozzo, M., De Rossi, A., Amadori, A., Callegaro, L., Siccardi, A. AIDS (1989) [Pubmed]
  3. Phorbol ester-induced modulation of cell surface antigens on U-937 cells in protein-free medium: effect of protein kinase and calmodulin inhibitors. Hunáková, L., Sedlák, J., Chorváth, B. Neoplasma (1993) [Pubmed]
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