Gene Review:
BLID - BH3-like motif containing, cell death inducer
Homo sapiens
Synonyms:
BH3-like motif-containing cell death inducer, BRCC2, Breast cancer cell protein 2
- BRCC2, a novel BH3-like domain-containing protein, induces apoptosis in a caspase-dependent manner. Broustas, C.G., Gokhale, P.C., Rahman, A., Dritschilo, A., Ahmad, I., Kasid, U. J. Biol. Chem. (2004)
- The proapoptotic molecule BLID interacts with Bcl-XL and its downregulation in breast cancer correlates with poor disease-free and overall survival. Broustas, C.G., Ross, J.S., Yang, Q., Sheehan, C.E., Riggins, R., Noone, A.M., Haddad, B.R., Seillier-Moiseiwitsch, F., Kallakury, B.V., Haffty, B.G., Clarke, R., Kasid, U.N. Clin. Cancer Res. (2010)