Chemical Compound Review:
boraniumyl boron(+1) trihydride cation
Synonyms:
CHEBI:30155, BH3(.+), [BH3](.+), trihydridoboron(.1+)
- Chlamydia inhibit host cell apoptosis by degradation of proapoptotic BH3-only proteins. Fischer, S.F., Vier, J., Kirschnek, S., Klos, A., Hess, S., Ying, S., Häcker, G. J. Exp. Med. (2004)
- BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alpha. Kim, J.Y., Ahn, H.J., Ryu, J.H., Suk, K., Park, J.H. J. Exp. Med. (2004)
- Involvement of BNIP1 in apoptosis and endoplasmic reticulum membrane fusion. Nakajima, K., Hirose, H., Taniguchi, M., Kurashina, H., Arasaki, K., Nagahama, M., Tani, K., Yamamoto, A., Tagaya, M. EMBO J. (2004)
- The Bik BH3-only protein is induced in estrogen-starved and antiestrogen-exposed breast cancer cells and provokes apoptosis. Hur, J., Chesnes, J., Coser, K.R., Lee, R.S., Geck, P., Isselbacher, K.J., Shioda, T. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Proapoptotic BH3-only Bcl-2 family member Bik/Blk/Nbk is expressed in hemopoietic and endothelial cells but is redundant for their programmed death. Coultas, L., Bouillet, P., Stanley, E.G., Brodnicki, T.C., Adams, J.M., Strasser, A. Mol. Cell. Biol. (2004)
- Control of apoptosis in the immune system: Bcl-2, BH3-only proteins and more. Marsden, V.S., Strasser, A. Annu. Rev. Immunol. (2003)
- BCL-2 family: regulators of cell death. Chao, D.T., Korsmeyer, S.J. Annu. Rev. Immunol. (1998)
- Proapoptotic BID is an ATM effector in the DNA-damage response. Kamer, I., Sarig, R., Zaltsman, Y., Niv, H., Oberkovitz, G., Regev, L., Haimovich, G., Lerenthal, Y., Marcellus, R.C., Gross, A. Cell (2005)
- A role for proapoptotic BID in the DNA-damage response. Zinkel, S.S., Hurov, K.E., Ong, C., Abtahi, F.M., Gross, A., Korsmeyer, S.J. Cell (2005)
- Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3. Lin, B., Kolluri, S.K., Lin, F., Liu, W., Han, Y.H., Cao, X., Dawson, M.I., Reed, J.C., Zhang, X.K. Cell (2004)
- Enhanced Killing of Melanoma Cells by Simultaneously Targeting Mcl-1 and NOXA. Qin, J.Z., Xin, H., Sitailo, L.A., Denning, M.F., Nickoloff, B.J. Cancer Res. (2006)
- The Secreted Protease Factor CPAF Is Responsible for Degrading Pro-apoptotic BH3-only Proteins in Chlamydia trachomatis-infected Cells. Pirbhai, M., Dong, F., Zhong, Y., Pan, K.Z., Zhong, G. J. Biol. Chem. (2006)
- Lovastatin-induced up-regulation of the BH3-only protein, Bim, and cell death in glioblastoma cells. Jiang, Z., Zheng, X., Lytle, R.A., Higashikubo, R., Rich, K.M. J. Neurochem. (2004)
- Beyond peroxisome proliferator-activated receptor gamma signaling: the multi-facets of the antitumor effect of thiazolidinediones. Weng, J.R., Chen, C.Y., Pinzone, J.J., Ringel, M.D., Chen, C.S. Endocr. Relat. Cancer (2006)
- The role of various Bcl-2 domains in the anti-proliferative effect and modulation of cellular glutathione levels: a prominent role for the BH4 domain. Hoetelmans, R.W., Vahrmeijer, A.L., van Vlierberghe, R.L., Keijzer, R., van de Velde, C.J., Mulder, G.J., Van Dierendonck, J.H. Cell Prolif. (2003)
- Solution structure of BID, an intracellular amplifier of apoptotic signaling. Chou, J.J., Li, H., Salvesen, G.S., Yuan, J., Wagner, G. Cell (1999)
- Conversion of Bcl-2 to a Bax-like death effector by caspases. Cheng, E.H., Kirsch, D.G., Clem, R.J., Ravi, R., Kastan, M.B., Bedi, A., Ueno, K., Hardwick, J.M. Science (1997)
- Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis. Puthalakath, H., Villunger, A., O'Reilly, L.A., Beaumont, J.G., Coultas, L., Cheney, R.E., Huang, D.C., Strasser, A. Science (2001)
- Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins. Willis, S.N., Chen, L., Dewson, G., Wei, A., Naik, E., Fletcher, J.I., Adams, J.M., Huang, D.C. Genes Dev. (2005)
- BID: a novel BH3 domain-only death agonist. Wang, K., Yin, X.M., Chao, D.T., Milliman, C.L., Korsmeyer, S.J. Genes Dev. (1996)
- Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane. Kuwana, T., Mackey, M.R., Perkins, G., Ellisman, M.H., Latterich, M., Schneiter, R., Green, D.R., Newmeyer, D.D. Cell (2002)
- Solution structure of the proapoptotic molecule BID: a structural basis for apoptotic agonists and antagonists. McDonnell, J.M., Fushman, D., Milliman, C.L., Korsmeyer, S.J., Cowburn, D. Cell (1999)
- The Noxa/Mcl-1 axis regulates susceptibility to apoptosis under glucose limitation in dividing T cells. Alves, N.L., Derks, I.A., Berk, E., Spijker, R., van Lier, R.A., Eldering, E. Immunity (2006)
- BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly. Kuwana, T., Bouchier-Hayes, L., Chipuk, J.E., Bonzon, C., Sullivan, B.A., Green, D.R., Newmeyer, D.D. Mol. Cell (2005)
- Bax deficiency partially corrects interleukin-7 receptor alpha deficiency. Khaled, A.R., Li, W.Q., Huang, J., Fry, T.J., Khaled, A.S., Mackall, C.L., Muegge, K., Young, H.A., Durum, S.K. Immunity (2002)
- harakiri, a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-X(L). Inohara, N., Ding, L., Chen, S., Núñez, G. EMBO J. (1997)
- Bcl-x(L) sequesters its C-terminal membrane anchor in soluble, cytosolic homodimers. Jeong, S.Y., Gaume, B., Lee, Y.J., Hsu, Y.T., Ryu, S.W., Yoon, S.H., Youle, R.J. EMBO J. (2004)
- Phosphorylation of BCL-2 regulates ER Ca2+ homeostasis and apoptosis. Bassik, M.C., Scorrano, L., Oakes, S.A., Pozzan, T., Korsmeyer, S.J. EMBO J. (2004)
- Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Luo, X., Budihardjo, I., Zou, H., Slaughter, C., Wang, X. Cell (1998)
- BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak. Zong, W.X., Lindsten, T., Ross, A.J., MacGregor, G.R., Thompson, C.B. Genes Dev. (2001)
- Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function. Chen, L., Willis, S.N., Wei, A., Smith, B.J., Fletcher, J.I., Hinds, M.G., Colman, P.M., Day, C.L., Adams, J.M., Huang, D.C. Mol. Cell (2005)
- Cytokines direct the regulation of bim mRNA stability by heat-shock cognate protein 70. Matsui, H., Asou, H., Inaba, T. Mol. Cell (2007)
- Proapoptotic BH3-only proteins trigger membrane integration of prosurvival Bcl-w and neutralize its activity. Wilson-Annan, J., O'Reilly, L.A., Crawford, S.A., Hausmann, G., Beaumont, J.G., Parma, L.P., Chen, L., Lackmann, M., Lithgow, T., Hinds, M.G., Day, C.L., Adams, J.M., Huang, D.C. J. Cell Biol. (2003)
- Mutagenesis of the BH3 domain of BAX identifies residues critical for dimerization and killing. Wang, K., Gross, A., Waksman, G., Korsmeyer, S.J. Mol. Cell. Biol. (1998)
- Dexamethasone resistance in B-cell precursor childhood acute lymphoblastic leukemia occurs downstream of ligand-induced nuclear translocation of the glucocorticoid receptor. Bachmann, P.S., Gorman, R., Mackenzie, K.L., Lutze-Mann, L., Lock, R.B. Blood (2005)
- c-Myc functionally cooperates with Bax to induce apoptosis. Juin, P., Hunt, A., Littlewood, T., Griffiths, B., Swigart, L.B., Korsmeyer, S., Evan, G. Mol. Cell. Biol. (2002)