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Gene Review

Pten  -  phosphatase and tensin homolog

Rattus norvegicus

Synonyms: MMAC1, Mmac, TEP1
 
 
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Disease relevance of Pten

  • These results suggest that alterations of the PTEN/MMAC1 gene may not be involved in the development of adenocarcinomas induced by BHP in rats [1].
 

High impact information on Pten

References

  1. Absence of PTEN/MMAC1 gene mutations in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats. Tsujiuchi, T., Sasaki, Y., Tsutsumi, M., Konishi, Y. Cancer Lett. (2001) [Pubmed]
  2. Essential role of Pten in body size determination and pancreatic beta-cell homeostasis in vivo. Nguyen, K.T., Tajmir, P., Lin, C.H., Liadis, N., Zhu, X.D., Eweida, M., Tolasa-Karaman, G., Cai, F., Wang, R., Kitamura, T., Belsham, D.D., Wheeler, M.B., Suzuki, A., Mak, T.W., Woo, M. Mol. Cell. Biol. (2006) [Pubmed]
 
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