Gene Review:
Pten - CG5671 gene product from transcript CG5671-RB
Drosophila melanogaster
Synonyms:
CG5671, DPTEN, Dmel\CG5671, PTEN, PTEN3, ...
- Mesangial cell hypertrophy by high glucose is mediated by downregulation of the tumor suppressor PTEN. Mahimainathan, L., Das, F., Venkatesan, B., Choudhury, G.G. Diabetes (2006)
- The PTEN/PI3K pathway governs normal vascular development and tumor angiogenesis. Hamada, K., Sasaki, T., Koni, P.A., Natsui, M., Kishimoto, H., Sasaki, J., Yajima, N., Horie, Y., Hasegawa, G., Naito, M., Miyazaki, J., Suda, T., Itoh, H., Nakao, K., Mak, T.W., Nakano, T., Suzuki, A. Genes Dev. (2005)
- Re-evaluating AKT regulation: role of TOR complex 2 in tissue growth. Hietakangas, V., Cohen, S.M. Genes Dev. (2007)
- Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway. Goberdhan, D.C., Paricio, N., Goodman, E.C., Mlodzik, M., Wilson, C. Genes Dev. (1999)
- The Drosophila insulin/IGF receptor controls growth and size by modulating PtdInsP(3) levels. Oldham, S., Stocker, H., Laffargue, M., Wittwer, F., Wymann, M., Hafen, E. Development (2002)
- A functional genomic analysis of cell morphology using RNA interference. Kiger, A.A., Baum, B., Jones, S., Jones, M.R., Coulson, A., Echeverri, C., Perrimon, N. J. Biol. (2003)
- Cytoplasmic activated protein kinase Akt regulates lipid-droplet accumulation in Drosophila nurse cells. Vereshchagina, N., Wilson, C. Development (2006)
- PTEN affects cell size, cell proliferation and apoptosis during Drosophila eye development. Huang, H., Potter, C.J., Tao, W., Li, D.M., Brogiolo, W., Hafen, E., Sun, H., Xu, T. Development (1999)
- The conserved PI3'K/PTEN/Akt signaling pathway regulates both cell size and survival in Drosophila. Scanga, S.E., Ruel, L., Binari, R.C., Snow, B., Stambolic, V., Bouchard, D., Peters, M., Calvieri, B., Mak, T.W., Woodgett, J.R., Manoukian, A.S. Oncogene (2000)
- Regulation of constitutive expression of mouse PTEN by the 5'-untranslated region. Han, B., Dong, Z., Liu, Y., Chen, Q., Hashimoto, K., Zhang, J.T. Oncogene (2003)
- Regulated and polarized PtdIns(3,4,5)P3 accumulation is essential for apical membrane morphogenesis in photoreceptor epithelial cells. Pinal, N., Goberdhan, D.C., Collinson, L., Fujita, Y., Cox, I.M., Wilson, C., Pichaud, F. Curr. Biol. (2006)
- A dual function for Deep orange in programmed autophagy in the Drosophila melanogaster fat body. Lindmo, K., Simonsen, A., Brech, A., Finley, K., Rusten, T.E., Stenmark, H. Exp. Cell Res. (2006)
- Regulation of the activity of the tumor suppressor PTEN by thioredoxin in Drosophila melanogaster. Song, Z., Saghafi, N., Gokhale, V., Brabant, M., Meuillet, E.J. Exp. Cell Res. (2007)
- Direct association of Bazooka/PAR-3 with the lipid phosphatase PTEN reveals a link between the PAR/aPKC complex and phosphoinositide signaling. von Stein, W., Ramrath, A., Grimm, A., Müller-Borg, M., Wodarz, A. Development (2005)