Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

fgf10 - fibroblast growth factor 10

Xenopus (Silurana) tropicalis

Yokoyama, H. et al., Yokoyama, H. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on fgf10

Exogenously applied FGF-10 successfully stimulated the regenerative capacity, resulting in the reinduction of all gene expressions (including shh, msx-1, and fgf-10) that we examined and the regeneration of well-patterned limb structures [1].
However, neither fgf-10 nor fgf-8 is reexpressed after amputation of a nonregenerative limb [2].
Mesenchyme with fgf-10 expression is responsible for regenerative capacity in Xenopus limb buds [2].

Analytical, diagnostic and therapeutic context of fgf10

By reciprocal transplantation experiments with regenerative and nonregenerative Xenopus limbs, we recently demonstrated that the regenerative capacity of a Xenopus limb depends on mesenchymal tissue and we suggested that fgf-10 is likely to be involved in this capacity (Yokoyama et al., 2000, Dev. Biol. 219, 18-29) [1].

References

FGF-10 stimulates limb regeneration ability in Xenopus laevis. Yokoyama, H., Ide, H., Tamura, K. Dev. Biol. (2001) [Pubmed]
Mesenchyme with fgf-10 expression is responsible for regenerative capacity in Xenopus limb buds. Yokoyama, H., Yonei-Tamura, S., Endo, T., Izpisúa Belmonte, J.C., Tamura, K., Ide, H. Dev. Biol. (2000) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

FGF10	Bos taurus
FGF10	Canis lupus familiaris
fgf10b	Danio rerio
fgf10a	Danio rerio
FGF10	Gallus gallus
FGF10	Homo sapiens
FGF10	Macaca mulatta
Fgf10	Mus musculus
FGF10	Pan troglodytes
Fgf10	Rattus norvegicus

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.