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Kcnt1  -  potassium channel, sodium-activated...

Rattus norvegicus

Synonyms: Potassium channel subfamily T member 1, Sequence like a calcium-activated potassium channel subunit, Slack, rSlo2
 
 
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High impact information on Kcnt1

  • As has also been shown for Slack, Slick is expressed in the olfactory bulb, red nucleus, facial nucleus, pontine nucleus, oculomotor nucleus, substantia nigra, deep cerebellar nuclei, vestibular nucleus, and the thalamus [1].
  • The antibody recognized Slack in transiently transfected CHO cells both by immunocytochemistry and by Western blot analysis [2].
  • Localization of the Slack potassium channel in the rat central nervous system [2].
  • Most prominent Slack immunoreactivity occurs in the brainstem, in particular the trigeminal system and reticular formation, where very intense staining was found in both cell bodies and axonal fibers of associated nuclei [2].
  • Ligaments were placed into six groups: Slack (n = 6 control, n = 6 healing), Reference (n = 4 control, n = 4 healing), Loaded (n = 4 control, n = 4 healing), 15 degrees Flexion (n = 4 control, n = 4 healing), 120 degrees Flexion (n = 4 control, n = 4 healing), and Tissue Strain vs. Flexion Angle (n = 8 normals) [3].
 

Anatomical context of Kcnt1

References

  1. Localization of the Na+-activated K+ channel Slick in the rat central nervous system. Bhattacharjee, A., von Hehn, C.A., Mei, X., Kaczmarek, L.K. J. Comp. Neurol. (2005) [Pubmed]
  2. Localization of the Slack potassium channel in the rat central nervous system. Bhattacharjee, A., Gan, L., Kaczmarek, L.K. J. Comp. Neurol. (2002) [Pubmed]
  3. Scanning electron microscopic characterization of healing and normal rat ligament microstructure under slack and loaded conditions. Hurschler, C., Provenzano, P.P., Vanderby, R. Connect. Tissue Res. (2003) [Pubmed]
 
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