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MeSH Review

Red Nucleus

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Disease relevance of Red Nucleus


High impact information on Red Nucleus

  • In order to localize a particular site of memory formation within the brain, the rabbit eyeblink response was classically conditioned while regions of the cerebellum or red nucleus were temporarily inactivated by microinfusions of the gamma-aminobutyric acid agonist muscimol [6].
  • We tested the relationship of the medial arc to oculomotor complex and red nucleus development by perturbing arc pattern formation in Sonic Hedgehog and FGF8 misexpression experiments [7].
  • We further found that FGF8 manipulations that push the medial arc rostrally coordinately move both the red nucleus and oculomotor complex anlagen [7].
  • Three months later the corticofugal projections to the red nucleus and the pons were analyzed; a relatively large number of corticorubral and corticopontine fibers from the lesioned side had crossed the midline and established an additional contralateral innervation of the red nucleus and the pons [8].
  • These results suggest that glutamatergic afferent input contributes significantly to the death of axotomized red nucleus and Clarke's nucleus neurons via NMDA receptors located on these neurons [9].

Biological context of Red Nucleus


Anatomical context of Red Nucleus


Associations of Red Nucleus with chemical compounds


Gene context of Red Nucleus


Analytical, diagnostic and therapeutic context of Red Nucleus


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  6. Localization of a memory trace in the mammalian brain. Krupa, D.J., Thompson, J.K., Thompson, R.F. Science (1993) [Pubmed]
  7. A role for midbrain arcs in nucleogenesis. Agarwala, S., Ragsdale, C.W. Development (2002) [Pubmed]
  8. Compensatory sprouting and impulse rerouting after unilateral pyramidal tract lesion in neonatal rats. Z'Graggen, W.J., Fouad, K., Raineteau, O., Metz, G.A., Schwab, M.E., Kartje, G.L. J. Neurosci. (2000) [Pubmed]
  9. NMDA receptor blockade rescues Clarke's and red nucleus neurons after spinal hemisection. Sanner, C.A., Cunningham, T.J., Goldberger, M.E. J. Neurosci. (1994) [Pubmed]
  10. Autoradiographical study of types 1 and 2 of benzodiazepine receptors in rat brain after chronic ethanol treatment and its withdrawal. Negro, M., Fernández-López, A., Calvo, P. Neuropharmacology (1995) [Pubmed]
  11. Improved choline acetyltransferase immunohistochemistry in the red nucleus by blocking the axonal transport. Onténiente, B., Condé, F. Behav. Brain Res. (1988) [Pubmed]
  12. Alterations of the nucleus ruber in 3-acetylpyridine intoxication. A light and electron microscopic study. Szalay, J., Böti, Z., Temesvári, P., Bara, D. Experimentelle Pathologie. (1979) [Pubmed]
  13. Bilateral alterations in local cerebral glucose utilization following intranigral application of the GABAergic agonist muscimol. Dermon, C.R., Pizarro, P., Georgopoulos, P., Savaki, H.E. J. Neurosci. (1990) [Pubmed]
  14. Regional distribution of neuropeptide Y and its receptor in the porcine central nervous system. Busch-Sørensen, M., Sheikh, S.P., O'Hare, M., Tortora, O., Schwartz, T.W., Gammeltoft, S. J. Neurochem. (1989) [Pubmed]
  15. A light microscopic investigation of the afferent connections of the lateral reticular nucleus in the cat. Hrycyshyn, A.W., Flumerfelt, B.A. J. Comp. Neurol. (1981) [Pubmed]
  16. Selective changes in local cerebral glucose utilization induced by phenobarbital in the rat. Hodes, J.E., Soncrant, T.T., Larson, D.M., Carlson, S.G., Rapoport, S.I. Anesthesiology (1985) [Pubmed]
  17. Sites of action of segmental and descending control of transmission on pathways mediating PAD of Ia- and Ib-afferent fibers in cat spinal cord. Rudomín, P., Jiménez, I., Solodkin, M., Dueñas, S. J. Neurophysiol. (1983) [Pubmed]
  18. Evidence for a role of haloperidol-sensitive sigma-'opiate' receptors in the motor effects of antipsychotic drugs. Walker, J.M., Matsumoto, R.R., Bowen, W.D., Gans, D.L., Jones, K.D., Walker, F.O. Neurology (1988) [Pubmed]
  19. Decreased release of D-aspartate in the guinea pig spinal cord after lesions of the red nucleus. Benson, C.G., Chase, M.C., Potashner, S.J. J. Neurochem. (1991) [Pubmed]
  20. Inhibition of classically conditioned eyeblink responses by stimulation of the cerebellar cortex in the decerebrate cat. Hesslow, G. J. Physiol. (Lond.) (1994) [Pubmed]
  21. GABA nerve endings in the rat red nucleus combined detection with serotonin terminals using dual immunocytochemistry. André, D., Vuillon-Cacciuttolo, G., Bosler, O. Neuroscience (1987) [Pubmed]
  22. Treatment of the chronically injured spinal cord with neurotrophic factors can promote axonal regeneration from supraspinal neurons. Ye, J.H., Houle, J.D. Exp. Neurol. (1997) [Pubmed]
  23. Mice with the deleted neurofilament of low-molecular-weight (Nefl) gene: 1. Effects on regional brain metabolism. Dubois, M., Lalonde, R., Julien, J.P., Strazielle, C. J. Neurosci. Res. (2005) [Pubmed]
  24. Calcium-binding proteins in the human developing brain. Ulfig, N. Advances in anatomy, embryology, and cell biology. (2002) [Pubmed]
  25. Heterogeneous distribution of neurons containing calbindin D-28k and/or parvalbumin in the rat red nucleus. Hontanilla, B., Parent, A., Giménez-Amaya, J.M. Brain Res. (1995) [Pubmed]
  26. Transplantation of genetically modified cells contributes to repair and recovery from spinal injury. Murray, M., Kim, D., Liu, Y., Tobias, C., Tessler, A., Fischer, I. Brain Res. Brain Res. Rev. (2002) [Pubmed]
  27. Identification and characterization of the murine and human gene encoding the tuberoinfundibular peptide of 39 residues. John, M.R., Arai, M., Rubin, D.A., Jonsson, K.B., Jüppner, H. Endocrinology (2002) [Pubmed]
  28. Glial fibrillary acidic protein expression in the hamster red nucleus: effects of axotomy and testosterone treatment. Storer, P.D., Jones, K.J. Exp. Neurol. (2003) [Pubmed]
  29. Functional connectivity between the red nucleus and the hippocampus supports the role of hippocampal formation in sensorimotor integration. Dypvik, A.T., Bland, B.H. J. Neurophysiol. (2004) [Pubmed]
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