The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Cerebellar Nuclei

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Cerebellar Nuclei


Psychiatry related information on Cerebellar Nuclei


High impact information on Cerebellar Nuclei

  • At stages prior to E12.5, with the exception of the deep cerebellar nuclei, we find that Math1 cells migrate out of the cerebellar primordium into the rostral hindbrain to populate specific nuclei that include cholinergic neurons of the mesopontine tegmental system [8].
  • Cerebellar ataxia, a devastating neurological disease, may be initiated by hyperexcitability of deep cerebellar nuclei (DCN) secondary to loss of inhibitory input from Purkinje neurons that frequently degenerate in this disease [9].
  • In cryostat sections, neurons that express proenkephalin include Golgi cells, macroneurons within deep cerebellar nuclei and a subpopulation of Purkinje cells [10].
  • Netrin-G1 transcripts were first detected in midbrain and hindbrain regions by embryonic day 12 and reached highest levels at perinatal stages in various brain regions, including olfactory bulb mitral cells, thalamus, and deep cerebellar nuclei [11].
  • In all 7 cases, elevated serotonin synthesis in the contralateral dentate nucleus was observed [12].

Chemical compound and disease context of Cerebellar Nuclei


Biological context of Cerebellar Nuclei


Anatomical context of Cerebellar Nuclei


Associations of Cerebellar Nuclei with chemical compounds


Gene context of Cerebellar Nuclei


Analytical, diagnostic and therapeutic context of Cerebellar Nuclei


  1. Kearns-Sayre syndrome: unusual pattern of expression of subunits of the respiratory chain in the cerebellar system. Tanji, K., Vu, T.H., Schon, E.A., DiMauro, S., Bonilla, E. Ann. Neurol. (1999) [Pubmed]
  2. Neural substrate of a cerebellar movement disorder induced by intracerebroventricular injection of propidium iodide in the rat: a Fos immunocytochemical study. Chen, S., Peng, Z.C., Bertini, G. Exp. Neurol. (1994) [Pubmed]
  3. Protective action of phenytoin in cerebral ischemia. Cullen, J.P., Aldrete, J.A., Jankovsky, L., Romo-Salas, F. Anesth. Analg. (1979) [Pubmed]
  4. Cerebellar degeneration in hereditary dentatorubral-pallidoluysian atrophy and Machado-Joseph disease. Kumada, S., Hayashi, M., Mizuguchi, M., Nakano, I., Morimatsu, Y., Oda, M. Acta Neuropathol. (2000) [Pubmed]
  5. Autism in tuberous sclerosis complex is related to both cortical and subcortical dysfunction. Asano, E., Chugani, D.C., Muzik, O., Behen, M., Janisse, J., Rothermel, R., Mangner, T.J., Chakraborty, P.K., Chugani, H.T. Neurology (2001) [Pubmed]
  6. Prion protein deposition and abnormal synaptic protein expression in the cerebellum in Creutzfeldt-Jakob disease. Ferrer, I., Puig, B., Blanco, R., Martí, E. Neuroscience (2000) [Pubmed]
  7. A non-familial Huntington's disease patient with grumose degeneration in the dentate nucleus. Ishikawa, A., Oyanagi, K., Tanaka, K., Igarashi, S., Sato, T., Tsuji, S. Acta neurologica Scandinavica. (1999) [Pubmed]
  8. Math1 is expressed in temporally discrete pools of cerebellar rhombic-lip neural progenitors. Machold, R., Fishell, G. Neuron (2005) [Pubmed]
  9. Enhanced neuronal excitability in the absence of neurodegeneration induces cerebellar ataxia. Shakkottai, V.G., Chou, C.H., Oddo, S., Sailer, C.A., Knaus, H.G., Gutman, G.A., Barish, M.E., LaFerla, F.M., Chandy, K.G. J. Clin. Invest. (2004) [Pubmed]
  10. A neuropeptide precursor in cerebellum: proenkephalin exists in subpopulations of both neurons and astrocytes. Spruce, B.A., Curtis, R., Wilkin, G.P., Glover, D.M. EMBO J. (1990) [Pubmed]
  11. Netrin-G1: a novel glycosyl phosphatidylinositol-linked mammalian netrin that is functionally divergent from classical netrins. Nakashiba, T., Ikeda, T., Nishimura, S., Tashiro, K., Honjo, T., Culotti, J.G., Itohara, S. J. Neurosci. (2000) [Pubmed]
  12. Altered serotonin synthesis in the dentatothalamocortical pathway in autistic boys. Chugani, D.C., Muzik, O., Rothermel, R., Behen, M., Chakraborty, P., Mangner, T., da Silva, E.A., Chugani, H.T. Ann. Neurol. (1997) [Pubmed]
  13. Peroxynitrite and caspase-3 expression after ischemia/reperfusion in mouse cardiac arrest model. Dohi, K., Ohtaki, H., Inn, R., Ikeda, Y., Shioda, H.S., Aruga, T. Acta Neurochir. Suppl. (2003) [Pubmed]
  14. Cerebellar excitatory and inhibitory amino acid receptors in multiple system atrophy. Price, R.H., Albin, R.L., Sakurai, S.Y., Polinsky, R.J., Penney, J.B., Young, A.B. Neurology (1993) [Pubmed]
  15. The projections of the lateral reticular nucleus to the deep cerebellar nuclei. An experimental analysis in the rat. Parenti, R., Cicirata, F., Pantò, M.R., Serapide, M.F. Eur. J. Neurosci. (1996) [Pubmed]
  16. Inferior olivary-induced expression of Fos-like immunoreactivity in the cerebellar nuclei of wild-type and Lurcher mice. Oldenbeuving, A.W., Eisenman, L.M., De Zeeuw, C.I., Ruigrok, T.J. Eur. J. Neurosci. (1999) [Pubmed]
  17. Regional distribution of 5-HT transporters in the brain of wild type and 'Purkinje cell degeneration' mutant mice: a quantitative autoradiographic study with [3H]citalopram. Le Marec, N., Hébert, C., Amdiss, F., Botez, M.I., Reader, T.A. J. Chem. Neuroanat. (1998) [Pubmed]
  18. Sulforhodamine labeling of neural circuits engaged in motor pattern generation in the in vitro turtle brainstem-cerebellum. Keifer, J., Vyas, D., Houk, J.C. J. Neurosci. (1992) [Pubmed]
  19. Neurotransmitter amino acids in dominantly inherited cerebellar disorders. Perry, T.L., Kish, S.J., Hansen, S., Currier, R.D. Neurology (1981) [Pubmed]
  20. Caspr3 and caspr4, two novel members of the caspr family are expressed in the nervous system and interact with PDZ domains. Spiegel, I., Salomon, D., Erne, B., Schaeren-Wiemers, N., Peles, E. Mol. Cell. Neurosci. (2002) [Pubmed]
  21. Girk2 expression in the ventral midbrain, cerebellum, and olfactory bulb and its relationship to the murine mutation weaver. Schein, J.C., Hunter, D.D., Roffler-Tarlov, S. Dev. Biol. (1998) [Pubmed]
  22. Decreased cerebellar 3',5'-cyclic guanosine monophosphate levels and insensitivity to harmaline in the genetically dystonic rat (dt). Lorden, J.F., Oltmans, G.A., McKeon, T.W., Lutes, J., Beales, M. J. Neurosci. (1985) [Pubmed]
  23. Neurochemical abnormalities in a patient with ataxia-telangiectasia. Perry, T.L., Kish, S.J., Hinton, D., Hansen, S., Becker, L.E., Gelfand, E.W. Neurology (1984) [Pubmed]
  24. Cerebellar diaschisis revisited: pontine hypometabolism and dentate sparing. Fulham, M.J., Brooks, R.A., Hallett, M., Di Chiro, G. Neurology (1992) [Pubmed]
  25. Electrical stimulation of cerebellar fastigial nucleus reduces ischemic infarction elicited by middle cerebral artery occlusion in rat. Reis, D.J., Berger, S.B., Underwood, M.D., Khayata, M. J. Cereb. Blood Flow Metab. (1991) [Pubmed]
  26. Ketamine effects on local cerebral blood flow and metabolism in the rat. Cavazzuti, M., Porro, C.A., Biral, G.P., Benassi, C., Barbieri, G.C. J. Cereb. Blood Flow Metab. (1987) [Pubmed]
  27. Dependence of parvalbumin expression on Purkinje cell input in the deep cerebellar nuclei. Bäurle, J., Hoshi, M., Grüsser-Cornehls, U. J. Comp. Neurol. (1998) [Pubmed]
  28. Differential distribution of Rac1 and Rac3 GTPases in the developing mouse brain: implications for a role of Rac3 in Purkinje cell differentiation. Bolis, A., Corbetta, S., Cioce, A., de Curtis, I. Eur. J. Neurosci. (2003) [Pubmed]
  29. Course and targets of the calbindin D-28k subpopulation of primary vestibular afferents. Bäurle, J., Vogten, H., Grüsser-Cornehls, U. J. Comp. Neurol. (1998) [Pubmed]
  30. Immunohistochemical distribution of the two isoforms of synaphin/complexin involved in neurotransmitter release: localization at the distinct central nervous system regions and synaptic types. Yamada, M., Saisu, H., Ishizuka, T., Takahashi, H., Abe, T. Neuroscience (1999) [Pubmed]
  31. Characteristic magnetic resonance imaging findings in spinocerebellar ataxia 6. Murata, Y., Kawakami, H., Yamaguchi, S., Nishimura, M., Kohriyama, T., Ishizaki, F., Matsuyama, Z., Mimori, Y., Nakamura, S. Arch. Neurol. (1998) [Pubmed]
  32. Opposing excitatory and inhibitory influences from the cerebellum and basal ganglia converge on the superior colliculus: an electrophysiological investigation in the rat. Westby, G.W., Collinson, C., Redgrave, P., Dean, P. Eur. J. Neurosci. (1994) [Pubmed]
  33. Neuron specific alpha-adrenergic receptor expression in human cerebellum: implications for emerging cerebellar roles in neurologic disease. Schambra, U.B., Mackensen, G.B., Stafford-Smith, M., Haines, D.E., Schwinn, D.A. Neuroscience (2005) [Pubmed]
  34. Autoradiographic mapping of local cerebral permeability to bilirubin in immature rats: effects of hyperbilirubinemia. Roger, C., Koziel, V., Vert, P., Nehlig, A. Pediatr. Res. (1996) [Pubmed]
  35. Neuronal and inducible nitric oxide synthase expression and protein nitration in rat cerebellum after oxygen and glucose deprivation. Rodrigo, J., Alonso, D., Fernández, A.P., Serrano, J., Richart, A., López, J.C., Santacana, M., Martínez-Murillo, R., Bentura, M.L., Ghiglione, M., Uttenthal, L.O. Brain Res. (2001) [Pubmed]
WikiGenes - Universities