Disease relevance of RPS15

• Plant cDNA homologue to rat insulinoma gene encoding ribosomal protein S15 [1].

High impact information on RPS15

• (ii) Transcripts of the rpo genes and of rps15, but not of genes involved in photosynthesis and related processes (psbA, rbcL, atpI-H), were abundantly accumulated in ribosome-deficient plastids [2].
• As a model system, the conformational changes of individual three-helix junction RNA molecules induced by the binding of ribosomal protein S15 or Mg(2+) ions were studied by changes in single-molecule fluorescence [3].
• A group of RNA binding proteins, termed tetraloop binding proteins, includes ribosomal protein S15 and protein SRP19 of signal recognition particle [4].
• The interaction between the ribosomal protein S15 and its binding sites in the 16S RNA was examined from two points of view [5].
• The amino acid sequence of ribosomal protein S15 purified from rat liver coincided with that deduced from the nucleotide sequence of rig mRNA, but there were indications that the initiator methionine was removed and the succeeding alanyl residue was monoacetylated [6].

Biological context of RPS15

• We have determined the nucleotide sequence and gene map location of the Xiphophorus maculatus homologue of RPS15 (ribosomal protein S15, alias RIG) [7].
• The Xiphophorus RPS15 cDNA encodes 145 amino acids, which show 94% identity compared to deduced mammalian and avian RPS15 amino acid sequences [7].
• Molecular mimicry in translational regulation: the case of ribosomal protein S15 [8].

Other interactions of RPS15

• Northern analysis revealed increases in the levels of clpP, rpl2, rpl23, rps15 and rpoB mRNAs in total RNA from albino leaves relative to those in green leaves [9].

References