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Gene Review

MSMO1  -  methylsterol monooxygenase 1

Homo sapiens

Synonyms: C-4 methylsterol oxidase, DESP4, ERG25, Methylsterol monooxygenase 1, SC4MOL
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High impact information on SC4MOL


Anatomical context of SC4MOL


Associations of SC4MOL with chemical compounds


Other interactions of SC4MOL

  • CONCLUSIONS: Our results indicate that LDL modulate ERG25 expression in the vascular wall and suggest the involvement of SREBP-2 in this mechanism [2].

Analytical, diagnostic and therapeutic context of SC4MOL

  • KTC exposure induced transcription of genes involved in lipid, fatty acid, and sterol metabolism, including ERG11, ERG3, ERG25, ERG6, ERG26, ERG24, ERG4, CPO, INO1, DW700960, CPR, DW696584, DW406350, and ATG15 [3].


  1. Characterization of yeast methyl sterol oxidase (ERG25) and identification of a human homologue. Li, L., Kaplan, J. J. Biol. Chem. (1996) [Pubmed]
  2. Modulation of ERG25 expression by LDL in vascular cells. Rodriguez, C., Raposo, B., Martínez-González, J., Llorente-Cortés, V., Vilahur, G., Badimon, L. Cardiovasc. Res. (2003) [Pubmed]
  3. Transcriptional Profiles of the Response to Ketoconazole and Amphotericin B in Trichophyton rubrum. Yu, L., Zhang, W., Wang, L., Yang, J., Liu, T., Peng, J., Leng, W., Chen, L., Li, R., Jin, Q. Antimicrob. Agents Chemother. (2007) [Pubmed]
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