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Chemical Compound Review

Allnal     2-[[(2S)-2-acetamido-4- methyl...

Synonyms: ALLN peptide, Cpi(1), LS-172106, AC1L33C2, C20H37N3O4, ...
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Disease relevance of Allnal


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Biological context of Allnal


Anatomical context of Allnal


Associations of Allnal with other chemical compounds


Gene context of Allnal


  1. Calpain is involved in the HIV replication from the latently infected OM10.1 cells. Teranishi, F., Liu, Z.Q., Kunimatsu, M., Imai, K., Takeyama, H., Manabe, T., Sasaki, M., Okamoto, T. Biochem. Biophys. Res. Commun. (2003) [Pubmed]
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  4. N- and C-terminal sequences control degradation of MAD3/I kappa B alpha in response to inducers of NF-kappa B activity. Whiteside, S.T., Ernst, M.K., LeBail, O., Laurent-Winter, C., Rice, N., Israël, A. Mol. Cell. Biol. (1995) [Pubmed]
  5. Role of glycogen synthase kinase 3beta in rapamycin-mediated cell cycle regulation and chemosensitivity. Dong, J., Peng, J., Zhang, H., Mondesire, W.H., Jian, W., Mills, G.B., Hung, M.C., Meric-Bernstam, F. Cancer Res. (2005) [Pubmed]
  6. Integrin alpha2-mediated ERK and calpain activation play a critical role in cell adhesion and motility via focal adhesion kinase signaling: identification of a novel signaling pathway. Sawhney, R.S., Cookson, M.M., Omar, Y., Hauser, J., Brattain, M.G. J. Biol. Chem. (2006) [Pubmed]
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  8. Modulation of ERG25 expression by LDL in vascular cells. Rodriguez, C., Raposo, B., Martínez-González, J., Llorente-Cortés, V., Vilahur, G., Badimon, L. Cardiovasc. Res. (2003) [Pubmed]
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  10. Ischemia promotes calpain-mediated degradation of p120-catenin in SH-SY5Y cells. Ohno, H., Uemura, K., Shintani-Ishida, K., Nakamura, M., Inomata, M., Yoshida, K. Biochem. Biophys. Res. Commun. (2007) [Pubmed]
  11. Accumulation and degradation in the endoplasmic reticulum of a truncated ER-60 devoid of C-terminal amino acid residues. Urade, R., Kusunose, M., Moriyama, T., Higasa, T., Kito, M. J. Biochem. (2000) [Pubmed]
  12. Peptide transport by the multidrug resistance pump. Sharma, R.C., Inoue, S., Roitelman, J., Schimke, R.T., Simoni, R.D. J. Biol. Chem. (1992) [Pubmed]
  13. Proteolysis and lipid-facilitated translocation are distinct but competitive processes that regulate secretion of apolipoprotein B in Hep G2 cells. Sakata, N., Wu, X., Dixon, J.L., Ginsberg, H.N. J. Biol. Chem. (1993) [Pubmed]
  14. Evidence that a rapidly turning over protein, normally degraded by proteasomes, regulates hsp72 gene transcription in HepG2 cells. Zhou, M., Wu, X., Ginsberg, H.N. J. Biol. Chem. (1996) [Pubmed]
  15. Chinese hamster ovary cells require the coexpression of microsomal triglyceride transfer protein and cholesterol 7alpha-hydroxylase for the assembly and secretion of apolipoprotein B-containing lipoproteins. Fleming, J.F., Spitsen, G.M., Hui, T.Y., Olivier, L., Du, E.Z., Raabe, M., Davis, R.A. J. Biol. Chem. (1999) [Pubmed]
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  17. c-Fos degradation by the proteasome. An early, Bcl-2-regulated step in apoptosis. He, H., Qi, X.M., Grossmann, J., Distelhorst, C.W. J. Biol. Chem. (1998) [Pubmed]
  18. Inhibition of calpain blocks pancreatic beta-cell spreading and insulin secretion. Parnaud, G., Hammar, E., Rouiller, D.G., Bosco, D. Am. J. Physiol. Endocrinol. Metab. (2005) [Pubmed]
  19. Enhancement of neurite outgrowth in PC12h cells by a protease inhibitor. Saito, Y., Kawashima, S. Neurosci. Lett. (1988) [Pubmed]
  20. Synergistic induction of apoptosis of rheumatoid arthritis synovial cells by H(2)O(2) and N-acetyl-leucyl-leucyl-norleucinal. Akaike, A., Banno, Y., Osawa, Y., Oshita, H., Fushimi, K., Kodama, H., Shimizu, K. Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association. (2003) [Pubmed]
  21. 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition prevents endothelial NO synthase downregulation by atherogenic levels of native LDLs: balance between transcriptional and posttranscriptional regulation. Martínez-González, J., Raposo, B., Rodríguez, C., Badimon, L. Arterioscler. Thromb. Vasc. Biol. (2001) [Pubmed]
  22. Overexpressed LEF-1 proteins display different nuclear localization patterns of beta-catenin in normal versus tumor cells. Ki, H., Jung, H.C., Park, J.H., Kim, J.S., Lee, K.Y., Kim, T.S., Kim, K. Cell Biol. Int. (2006) [Pubmed]
  23. Sterol regulatory element-binding protein-1a binds to cis elements in the promoter of the rat high density lipoprotein receptor SR-BI gene. Lopez, D., McLean, M.P. Endocrinology (1999) [Pubmed]
  24. Hydrogen peroxide activates NF-kappa B through tyrosine phosphorylation of I kappa B alpha and serine phosphorylation of p65: evidence for the involvement of I kappa B alpha kinase and Syk protein-tyrosine kinase. Takada, Y., Mukhopadhyay, A., Kundu, G.C., Mahabeleshwar, G.H., Singh, S., Aggarwal, B.B. J. Biol. Chem. (2003) [Pubmed]
  25. Blocking intracellular degradation of the erythropoietin and asialoglycoprotein receptors by calpain inhibitors does not result in the same increase in the levels of their membrane and secreted forms. Neumann, D., Yuk, M.H., Lodish, H.F., Lederkremer, G.Z. Biochem. J. (1996) [Pubmed]
  26. Interleukin-1beta and interleukin-6 increase levels of apolipoprotein B mRNA and decrease accumulation of its protein in culture medium of HepG2 cells. Yokoyama, K., Ishibashi, T., Yi-qiang, L., Nagayoshi, A., Teramoto, T., Maruyama, Y. J. Lipid Res. (1998) [Pubmed]
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