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Gene Review

Suv39h2  -  suppressor of variegation 3-9 homolog 2...

Mus musculus

Synonyms: 4930507K23Rik, AA536750, D030054H19Rik, D2Ertd544e, H3-K9-HMTase 2, ...
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High impact information on Suv39h2


Anatomical context of Suv39h2

  • These data are consistent with redundant enzymatic roles for Suv39h1 and Suv39h2 during mouse development and suggest an additional function of the Suv39h2 HMTase in organizing meiotic heterochromatin that may even impart an epigenetic imprint to the male germ line [2].


  1. Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases. García-Cao, M., O'Sullivan, R., Peters, A.H., Jenuwein, T., Blasco, M.A. Nat. Genet. (2004) [Pubmed]
  2. Isolation and characterization of Suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expression. O'Carroll, D., Scherthan, H., Peters, A.H., Opravil, S., Haynes, A.R., Laible, G., Rea, S., Schmid, M., Lebersorger, A., Jerratsch, M., Sattler, L., Mattei, M.G., Denny, P., Brown, S.D., Schweizer, D., Jenuwein, T. Mol. Cell. Biol. (2000) [Pubmed]
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