The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Links

 

Gene Review

Spag16  -  sperm associated antigen 16

Mus musculus

Synonyms: 4921511D23Rik, 4930524F24Rik, 4930585K05Rik, AV261009, Pf20, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

High impact information on Spag16

 

Biological context of Spag16

  • The different patterns of expression of the two PF20 proteins suggest the possibility that the Pf20 gene has multiple functions during spermatogenesis [1].
  • The murine Pf20 gene was mapped to chromosome 1, syntenic with the location of the human gene on chromosome 2 [2].
  • The sperm defect is consistent with the motility phenotype of the Pf20 mutants of Chlamydomonas, but morphologically different in that the mutant algal axoneme lacks the central apparatus [3].
 

Analytical, diagnostic and therapeutic context of Spag16

References

  1. Haploinsufficiency for the murine orthologue of Chlamydomonas PF20 disrupts spermatogenesis. Zhang, Z., Kostetskii, I., Moss, S.B., Jones, B.H., Ho, C., Wang, H., Kishida, T., Gerton, G.L., Radice, G.L., Strauss, J.F. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  2. A sperm-associated WD repeat protein orthologous to Chlamydomonas PF20 associates with Spag6, the mammalian orthologue of Chlamydomonas PF16. Zhang, Z., Sapiro, R., Kapfhamer, D., Bucan, M., Bray, J., Chennathukuzhi, V., McNamara, P., Curtis, A., Zhang, M., Blanchette-Mackie, E.J., Strauss, J.F. Mol. Cell. Biol. (2002) [Pubmed]
  3. Deficiency of SPAG16L causes male infertility associated with impaired sperm motility. Zhang, Z., Kostetskii, I., Tang, W., Haig-Ladewig, L., Sapiro, R., Wei, Z., Patel, A.M., Bennett, J., Gerton, G.L., Moss, S.B., Radice, G.L., Strauss, J.F. Biol. Reprod. (2006) [Pubmed]
 
WikiGenes - Universities