Disease relevance of CYTB

• To evaluate the host-feeding patterns of Aedes vexans (Meigen) and Culiseta melanura (Coquillett) as secondary vectors of West Nile virus (family Flaviviridae, genus Flavivirus, WNV) in Northeastern United States, we identified the source of vertebrate bloodmeals by sequencing portions of the cytochrome b gene of mitochondrial DNA [1].

High impact information on CYTB

• Molecular phylogeny of mitochondrial cytochrome b and 12S rRNA sequences in the Felidae: ocelot and domestic cat lineages [2].
• Sequence analyses of 363 bp of cytochrome b and 376 bp of the 12S rRNA genes yielded average pair-wise similarity values between felids ranging from 94 to 99% and from 85 to 99%, respectively [2].
• Molecular phylogeny of the cat family Felidae is derived using two mitochondrial genes, cytochrome b and 12S rRNA [2].
• Nucleotide sequences obtained from the PCR products corresponded with cytochrome b sequences of the carnivore species expected [3].
• Based on DNA sequence data from previous phylogenetic studies, we designed species-specific primers for polymerase chain reaction (PCR) amplification of the partial mitochondrial cytochrome b gene (112-347 bp) to identify the species and primers for the partial SRY gene (135 bp) to determine the sex [3].

Biological context of CYTB

• To investigate the molecular phylogenetic status of the Iriomote cat Felis iriomotensis, partial sequences of the mitochondrial 12S rRNA gene (373 bases) and the cytochrome b gene (402 bases) were determined by using the polymerase chain reaction-product direct sequencing technique and then compared with those of seven other feline species [4].
• In the cats, six haplotypes of the complete cytochrome b sequences (1,140 base-pairs, bp) and ten haplotypes of the partial control region sequences (350 bp) were identified [5].

References