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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


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Disease relevance of Cats


High impact information on Cats


Chemical compound and disease context of Cats


Biological context of Cats


Anatomical context of Cats


Associations of Cats with chemical compounds


Gene context of Cats

  • Deficiency of cytosolic arylamine N-acetylation in the domestic cat and wild felids caused by the presence of a single NAT1-like gene [30].
  • TYRP1 was mapped on chromosome D4 within 5 cM of a highly polymorphic microsatellite, previously found to be fixed in a cat breed selected for the chocolate (b) allele of the B locus, which reinforced TYRP1 as a candidate gene for the B locus in the domestic cat [31].
  • Chromosomal mapping of enzyme loci in the domestic cat: GSR to C2, ADA and ITPA to A3, and LDHA-ACP2 to D1 [32].
  • Demonstration of biological activity of CD40 ligand (CD154) in the domestic cat [33].
  • Tas1r2 in tiger and cheetah and in six healthy adult domestic cats all show the similar deletion and stop codons [34].

Analytical, diagnostic and therapeutic context of Cats


  1. Feline muscular dystrophy with dystrophin deficiency. Carpenter, J.L., Hoffman, E.P., Romanul, F.C., Kunkel, L.M., Rosales, R.K., Ma, N.S., Dasbach, J.J., Rae, J.F., Moore, F.M., McAfee, M.B. Am. J. Pathol. (1989) [Pubmed]
  2. Puma lentivirus is controlled in domestic cats after mucosal exposure in the absence of conventional indicators of immunity. Terwee, J.A., Yactor, J.K., Sondgeroth, K.S., Vandewoude, S. J. Virol. (2005) [Pubmed]
  3. A lion lentivirus related to feline immunodeficiency virus: epidemiologic and phylogenetic aspects. Brown, E.W., Yuhki, N., Packer, C., O'Brien, S.J. J. Virol. (1994) [Pubmed]
  4. Pathogenesis of feline diabetes mellitus. O'Brien, T.D. Mol. Cell. Endocrinol. (2002) [Pubmed]
  5. Associations amongst three feline Porphyromonas species from the gingival margin of cats during periodontal health and disease. Norris, J.M., Love, D.N. Vet. Microbiol. (1999) [Pubmed]
  6. Cat is a major allergen in patients with asthma from west Siberia, Russia. Gusareva, E.S., Bragina, E.J., Deeva, E.V., Kazakevich, N.V., Puzyrev, V.P., Ogorodova, L.M., Lipoldová, M. Allergy. (2006) [Pubmed]
  7. Primary plague pneumonia contracted from a domestic cat at South Lake Tahoe, Calif. Werner, S.B., Weidmer, C.E., Nelson, B.C., Nygaard, G.S., Goethals, R.M., Poland, J.D. JAMA (1984) [Pubmed]
  8. A mutation in the lipoprotein lipase gene is the molecular basis of chylomicronemia in a colony of domestic cats. Ginzinger, D.G., Lewis, M.E., Ma, Y., Jones, B.R., Liu, G., Jones, S.D. J. Clin. Invest. (1996) [Pubmed]
  9. Amino acid sequence of Fel dI, the major allergen of the domestic cat: protein sequence analysis and cDNA cloning. Morgenstern, J.P., Griffith, I.J., Brauer, A.W., Rogers, B.L., Bond, J.F., Chapman, M.D., Kuo, M.C. Proc. Natl. Acad. Sci. U.S.A. (1991) [Pubmed]
  10. Characterization of glucocorticoid receptors in animal lymphoblastic disease: correlation with response to single-agent glucocorticoid treatment. Bell, R., Cotter, S., Lillquist, A., Sallan, S., McCaffrey, R. Blood (1984) [Pubmed]
  11. Isolation and characterization of a felinine-containing peptide from the blood of the domestic cat (Felis catus). Rutherfurd, K.J., Rutherfurd, S.M., Moughan, P.J., Hendriks, W.H. J. Biol. Chem. (2002) [Pubmed]
  12. Comparison of serum and plasma taurine values in Bengal tigers with values in taurine-sufficient and -deficient domestic cats. Pickett, J.P., Chesney, R.W., Beehler, B., Moore, C.P., Lippincott, S., Sturman, J., Ketring, K.L. J. Am. Vet. Med. Assoc. (1990) [Pubmed]
  13. Effects of weight gain and loss on metabolic rate, glucose tolerance, and serum lipids in domestic cats. Fettman, M.J., Stanton, C.A., Banks, L.L., Johnson, D.E., Hamar, D.W., Hegstad, R.L., Johnston, S. Res. Vet. Sci. (1998) [Pubmed]
  14. The domestic cat as a host for Brugian filariasis in South Kalimantan (Borneo), Indonesia. Palmieri, J.R., Masbar, S., Purnomo, n.u.l.l., Marwoto, H.A., Tirtokusumo, S., Darwis, F. J. Helminthol. (1985) [Pubmed]
  15. In vivo pharmacokinetics and toxicity profile of the anti-HIV agent stampidine in dogs and feline immunodeficiency virus-infected cats. Uckun, F.M., Waurzyniak, B., Tibbles, H., Venkatachalam, T.K., Erbeck, D. Arzneimittel-Forschung. (2006) [Pubmed]
  16. Molecular screening by polymerase chain reaction detects panleukopenia virus DNA in formalin-fixed hearts from cats with idiopathic cardiomyopathy and myocarditis. Meurs, K.M., Fox, P.R., Magnon, A.L., Liu, S., Towbin, J.A. Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology. (2000) [Pubmed]
  17. Characterization of MHC cDNA clones in the domestic cat. Diversity and evolution of class I genes. Yuhki, N., Heidecker, G.F., O'Brien, S.J. J. Immunol. (1989) [Pubmed]
  18. Diet-induced atherosclerosis in the domestic cat. Ginzinger, D.G., Wilson, J.E., Redenbach, D., Lewis, M.E., Clee, S.M., Excoffon, K.J., Rogers, Q.R., Hayden, M.R., McManus, B.M. Lab. Invest. (1997) [Pubmed]
  19. Luteal function in the domestic cat during pseudopregnancy and after treatment with prostaglandin F2 alpha. Shille, V.M., Stabenfeldt, G.H. Biol. Reprod. (1979) [Pubmed]
  20. Proviral organization and sequence analysis of feline immunodeficiency virus isolated from a Pallas' cat. Barr, M.C., Zou, L., Long, F., Hoose, W.A., Avery, R.J. Virology (1997) [Pubmed]
  21. Molecular phylogeny of mitochondrial cytochrome b and 12S rRNA sequences in the Felidae: ocelot and domestic cat lineages. Masuda, R., Lopez, J.V., Slattery, J.P., Yuhki, N., O'Brien, S.J. Mol. Phylogenet. Evol. (1996) [Pubmed]
  22. Definition of the human T-cell epitopes of Fel d 1, the major allergen of the domestic cat. Counsell, C.M., Bond, J.F., Ohman, J.L., Greenstein, J.L., Garman, R.D. J. Allergy Clin. Immunol. (1996) [Pubmed]
  23. Thyroid hormone deiodination in the domestic cat. Foster, D.J., Thoday, K.L., Beckett, G.J. J. Mol. Endocrinol. (2000) [Pubmed]
  24. The effect of cavity preparation on the metabolism of protein in dentin. Hoppenbrouwers, P.M., Borggreven, J.M., Thé, G.S., Maltha, J.C. J. Dent. Res. (1982) [Pubmed]
  25. Dietary beta-carotene absorption by blood plasma and leukocytes in domestic cats. Chew, B.P., Park, J.S., Weng, B.C., Wong, T.S., Hayek, M.G., Reinhart, G.A. J. Nutr. (2000) [Pubmed]
  26. Relative effects of pentobarbital and chloralose on the responsiveness of neurons in sensorimotor cerebral cortex of the domestic cat. Harding, G.W., Stogsdill, R.M., Towe, A.L. Neuroscience (1979) [Pubmed]
  27. Nature and origin of polymorphism in feline MHC class II DRA and DRB genes. Yuhki, N., O'Brien, S.J. J. Immunol. (1997) [Pubmed]
  28. Identification of pyridoxine 3-sulfate, pyridoxal 3-sulfate, and N-methylpyridoxine as major urinary metabolites of vitamin B6 in domestic cats. Coburn, S.P., Mahuren, J.D. J. Biol. Chem. (1987) [Pubmed]
  29. A feline model of experimentally induced islet amyloidosis. Hoenig, M., Hall, G., Ferguson, D., Jordan, K., Henson, M., Johnson, K., O'Brien, T. Am. J. Pathol. (2000) [Pubmed]
  30. Deficiency of cytosolic arylamine N-acetylation in the domestic cat and wild felids caused by the presence of a single NAT1-like gene. Trepanier, L.A., Cribb, A.E., Spielberg, S.P., Ray, K. Pharmacogenetics (1998) [Pubmed]
  31. Tyrosinase and tyrosinase related protein 1 alleles specify domestic cat coat color phenotypes of the albino and brown loci. Schmidt-Küntzel, A., Eizirik, E., O'Brien, S.J., Menotti-Raymond, M. J. Hered. (2005) [Pubmed]
  32. Chromosomal mapping of enzyme loci in the domestic cat: GSR to C2, ADA and ITPA to A3, and LDHA-ACP2 to D1. Berman, E.J., Nash, W.G., Seuánez, H.N., O'Brien, S.J. Cytogenet. Cell Genet. (1986) [Pubmed]
  33. Demonstration of biological activity of CD40 ligand (CD154) in the domestic cat. Brown, A.L., Dunsford, T.H., Jarrett, O., Willett, B.J., Hosie, M.J. Cytokine (2002) [Pubmed]
  34. Pseudogenization of a sweet-receptor gene accounts for cats' indifference toward sugar. Li, X., Li, W., Wang, H., Cao, J., Maehashi, K., Huang, L., Bachmanov, A.A., Reed, D.R., Legrand-Defretin, V., Beauchamp, G.K., Brand, J.G. PLoS Genet. (2005) [Pubmed]
  35. Comparative aspects of steroid hormone metabolism and ovarian activity in felids, measured noninvasively in feces. Brown, J.L., Wasser, S.K., Wildt, D.E., Graham, L.H. Biol. Reprod. (1994) [Pubmed]
  36. Effects of equine chorionic gonadotropin, human chorionic gonadotropin, and laparoscopic artificial insemination on embryo, endocrine, and luteal characteristics in the domestic cat. Roth, T.L., Wolfe, B.A., Long, J.A., Howard, J.G., Wildt, D.E. Biol. Reprod. (1997) [Pubmed]
  37. The renal excretion of iodine following oral administration of Gastrografin to domestic cats. Allan, G.S., Wentworth, R.A., Rendano, V.T., Meunier, P.C., Marmor, M. Investigative radiology. (1980) [Pubmed]
  38. Sequence analysis of MHC DRB alleles in domestic cats from the United Kingdom. Kennedy, L.J., Ryvar, R., Gaskell, R.M., Addie, D.D., Willoughby, K., Carter, S.D., Thomson, W., Ollier, W.E., Radford, A.D. Immunogenetics (2002) [Pubmed]
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