The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

CYP98A3  -  cytochrome P450 98A3

Arabidopsis thaliana

Synonyms: T20B5.9, T20B5_9, cytochrome P450, family 98, polypeptide 3, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on CYP98A3


Biological context of CYP98A3

  • In transgenic Arabidopsis, the promoters of CYP98A3 and C4H showed wound inducibility and a comparable developmental regulation throughout the life cycle, except in seeds, where the CYP98A3 promoter construct was inactive while remaining active in silique walls [3].
  • Finally, the mutant displays developmental defects and is subject to fungal attack, suggesting that phenylpropanoid pathway products downstream of REF8 may be required for normal plant development and disease resistance [4].

Associations of CYP98A3 with chemical compounds


  1. CYP98A3 from Arabidopsis thaliana is a 3'-hydroxylase of phenolic esters, a missing link in the phenylpropanoid pathway. Schoch, G., Goepfert, S., Morant, M., Hehn, A., Meyer, D., Ullmann, P., Werck-Reichhart, D. J. Biol. Chem. (2001) [Pubmed]
  2. A coumaroyl-ester-3-hydroxylase insertion mutant reveals the existence of nonredundant meta-hydroxylation pathways and essential roles for phenolic precursors in cell expansion and plant growth. Abdulrazzak, N., Pollet, B., Ehlting, J., Larsen, K., Asnaghi, C., Ronseau, S., Proux, C., Erhardt, M., Seltzer, V., Renou, J.P., Ullmann, P., Pauly, M., Lapierre, C., Werck-Reichhart, D. Plant Physiol. (2006) [Pubmed]
  3. Arabidopsis CYP98A3 mediating aromatic 3-hydroxylation. Developmental regulation of the gene, and expression in yeast. Nair, R.B., Xia, Q., Kartha, C.J., Kurylo, E., Hirji, R.N., Datla, R., Selvaraj, G. Plant Physiol. (2002) [Pubmed]
  4. Changes in secondary metabolism and deposition of an unusual lignin in the ref8 mutant of Arabidopsis. Franke, R., Hemm, M.R., Denault, J.W., Ruegger, M.O., Humphreys, J.M., Chapple, C. Plant J. (2002) [Pubmed]
  5. Accumulation of coumarins in Arabidopsis thaliana. Kai, K., Shimizu, B., Mizutani, M., Watanabe, K., Sakata, K. Phytochemistry (2006) [Pubmed]
WikiGenes - Universities