Disease relevance of SAL1

• The fry1 plants showed enhanced induction of stress genes in response to cold, ABA, salt and dehydration due to higher accumulation of the second messenger, inositol (1,4,5)- triphosphate (IP(3)) [1].

High impact information on SAL1

• Upon ABA treatment, fry1 mutant plants accumulated more IP(3) than did the wild-type plants [2].
• FIERY1 encoding an inositol polyphosphate 1-phosphatase is a negative regulator of abscisic acid and stress signaling in Arabidopsis [2].
• Map-based cloning revealed that FRY1 encodes an inositol polyphosphate 1-phosphatase, which functions in the catabolism of inositol 1, 4, 5-trisphosphate (IP(3)) [2].
• We propose that the product of SAL1 participates in the sulfur assimilation pathway as well as in the phosphoinositide signaling pathway and that changes in the latter may affect Na+ and Li+ fluxes [3].
• FIERY1 is a general negative regulator that controls cold, osmotic stress, and ABA signal transduction and possesses inositol polyphosphate 1-phosphatase activity [4].

Biological context of SAL1

• These results indicate that HOS2 is a negative regulator of low temperature signal transduction important for plant cold acclimation [5].
• Gene expression in response to osmotic stress or ABA is not affected in the hos2 mutants [5].
• A single amino acid substitution in the Arabidopsis FIERY1/HOS2 protein confers cold signaling specificity and lithium tolerance [4].
• The presence of more than 10 isoforms of PIPK, PLC, PLD and IPPase suggested that these genes might be differentially expressed during plant cellular responses or growth and development [6].

References