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Gene Review

DWF5  -  7-dehydrocholesterol reductase

Arabidopsis thaliana

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Disease relevance of DWF5


High impact information on DWF5


  1. Lesions in the sterol delta reductase gene of Arabidopsis cause dwarfism due to a block in brassinosteroid biosynthesis. Choe, S., Tanaka, A., Noguchi, T., Fujioka, S., Takatsuto, S., Ross, A.S., Tax, F.E., Yoshida, S., Feldmann, K.A. Plant J. (2000) [Pubmed]
  2. Characterisation of the telomeres at opposite ends of a 3 Mb Theileria parva chromosome. Sohanpal, B.K., Morzaria, S.P., Gobright, E.I., Bishop, R.P. Nucleic Acids Res. (1995) [Pubmed]
  3. Smith-Lemli-Opitz syndrome is caused by mutations in the 7-dehydrocholesterol reductase gene. Waterham, H.R., Wijburg, F.A., Hennekam, R.C., Vreken, P., Poll-The, B.T., Dorland, L., Duran, M., Jira, P.E., Smeitink, J.A., Wevers, R.A., Wanders, R.J. Am. J. Hum. Genet. (1998) [Pubmed]
  4. Mutations in the human sterol delta7-reductase gene at 11q12-13 cause Smith-Lemli-Opitz syndrome. Wassif, C.A., Maslen, C., Kachilele-Linjewile, S., Lin, D., Linck, L.M., Connor, W.E., Steiner, R.D., Porter, F.D. Am. J. Hum. Genet. (1998) [Pubmed]
  5. New perspectives on proanthocyanidin biochemistry and molecular regulation. Marles, M.A., Ray, H., Gruber, M.Y. Phytochemistry (2003) [Pubmed]
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