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Gene Review

MYO18B  -  myosin XVIIIB

Homo sapiens

Synonyms: BK125H2.1, Unconventional myosin-XVIIIb
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Disease relevance of MYO18B


High impact information on MYO18B


Biological context of MYO18B


Anatomical context of MYO18B


Associations of MYO18B with chemical compounds


Other interactions of MYO18B


Analytical, diagnostic and therapeutic context of MYO18B


  1. MYO18B, a candidate tumor suppressor gene at chromosome 22q12.1, deleted, mutated, and methylated in human lung cancer. Nishioka, M., Kohno, T., Tani, M., Yanaihara, N., Tomizawa, Y., Otsuka, A., Sasaki, S., Kobayashi, K., Niki, T., Maeshima, A., Sekido, Y., Minna, J.D., Sone, S., Yokota, J. Proc. Natl. Acad. Sci. U.S.A. (2002) [Pubmed]
  2. Reduced expression of MYO18B, a candidate tumor-suppressor gene on chromosome arm 22q, in ovarian cancer. Yanaihara, N., Nishioka, M., Kohno, T., Otsuka, A., Okamoto, A., Ochiai, K., Tanaka, T., Yokota, J. Int. J. Cancer (2004) [Pubmed]
  3. Genetic and epigenetic alterations of the candidate tumor-suppressor gene MYO18B, on chromosome arm 22q, in colorectal cancer. Nakano, T., Tani, M., Nishioka, M., Kohno, T., Otsuka, A., Ohwada, S., Yokota, J. Genes Chromosomes Cancer (2005) [Pubmed]
  4. Human MYO18B, a novel unconventional myosin heavy chain expressed in striated muscles moves into the myonuclei upon differentiation. Salamon, M., Millino, C., Raffaello, A., Mongillo, M., Sandri, C., Bean, C., Negrisolo, E., Pallavicini, A., Valle, G., Zaccolo, M., Schiaffino, S., Lanfranchi, G. J. Mol. Biol. (2003) [Pubmed]
  5. Correlation between histone acetylation and expression of the MYO18B gene in human lung cancer cells. Tani, M., Ito, J., Nishioka, M., Kohno, T., Tachibana, K., Shiraishi, M., Takenoshita, S., Yokota, J. Genes Chromosomes Cancer (2004) [Pubmed]
  6. MYO18B interacts with the proteasomal subunit Sug1 and is degraded by the ubiquitin-proteasome pathway. Inoue, T., Kon, T., Ajima, R., Ohkura, R., Tani, M., Yokota, J., Sutoh, K. Biochem. Biophys. Res. Commun. (2006) [Pubmed]
  7. Genetic alterations responsible for metastatic phenotypes of lung cancer cells. Yokota, J., Nishioka, M., Tani, M., Kohno, T. Clin. Exp. Metastasis (2003) [Pubmed]
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