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Gene Review

SMP1  -  Smp1p

Saccharomyces cerevisiae S288c

Synonyms: Transcription factor SMP1, YBR1245, YBR182C
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High impact information on SMP1

  • Localization of Smp1 depends on HOG1, and consistently, hog1Delta cells also lose viability during this growth phase [1].
  • Phosphorylation of Smp1 by the MAPK is essential for its function, since a mutant allele unable to be phosphorylated by the MAPK displays impaired stress responses [1].
  • Deletion mutations of the Rim101p repression targets NRG1 and SMP1 suppress rim101Delta mutant defects in ion tolerance, haploid invasive growth, and sporulation [2].
  • Deletion of SMP1 neither causes these phenotypes nor enhances the Rlm1 deletion phenotype [3].
  • The open reading frame (ORF) YBR1245 is similar in its N-terminal part to transcription factors like SRF and MCM1 [4].

Biological context of SMP1


Anatomical context of SMP1


Enzymatic interactions of SMP1


Other interactions of SMP1

  • Like MEF2A, the yeast proteins Rlm1 and Smp1 exhibit low DNA bending propensities [6].


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