Gene Review:
PUS1 - pseudouridine synthase PUS1
Saccharomyces cerevisiae S288c
Synonyms:
YPL212C, tRNA pseudouridine synthase 1, tRNA pseudouridylate synthase 1, tRNA-uridine isomerase 1
- Pseudouridine synthetase Pus1 of Saccharomyces cerevisiae: kinetic characterisation, tRNA structural requirement and real-time analysis of its complex with tRNA. Arluison, V., Buckle, M., Grosjean, H. J. Mol. Biol. (1999)
- Pseudouridylation of yeast U2 snRNA is catalyzed by either an RNA-guided or RNA-independent mechanism. Ma, X., Yang, C., Alexandrov, A., Grayhack, E.J., Behm-Ansmant, I., Yu, Y.T. EMBO J. (2005)
- Nuclear pore proteins are involved in the biogenesis of functional tRNA. Simos, G., Tekotte, H., Grosjean, H., Segref, A., Sharma, K., Tollervey, D., Hurt, E.C. EMBO J. (1996)
- Pseudouridine mapping in the Saccharomyces cerevisiae spliceosomal U small nuclear RNAs (snRNAs) reveals that pseudouridine synthase pus1p exhibits a dual substrate specificity for U2 snRNA and tRNA. Massenet, S., Motorin, Y., Lafontaine, D.L., Hurt, E.C., Grosjean, H., Branlant, C. Mol. Cell. Biol. (1999)
- Pus1p-dependent tRNA pseudouridinylation becomes essential when tRNA biogenesis is compromised in yeast. Grosshans, H., Lecointe, F., Grosjean, H., Hurt, E., Simos, G. J. Biol. Chem. (2001)
- A gene tightly linked to CEN6 is important for growth of Saccharomyces cerevisiae. Carbone, M.L., Solinas, M., Sora, S., Panzeri, L. Curr. Genet. (1991)
- The yeast tRNA:pseudouridine synthase Pus1p displays a multisite substrate specificity. Motorin, Y., Keith, G., Simon, C., Foiret, D., Simos, G., Hurt, E., Grosjean, H. RNA (1998)