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Gene Review

CACNA1G  -  calcium channel, voltage-dependent, T type...

Homo sapiens

Synonyms: Ca(V)T.1, Cav3.1, Cav3.1c, KIAA1123, NBR13, ...
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Disease relevance of CACNA1G


High impact information on CACNA1G


Biological context of CACNA1G


Other interactions of CACNA1G

  • We then used this fragment to screen human heart and rat brain lambda gt10 libraries, leading to the cloning of two full-length cDNAs derived from distinct genes (CACNA1G and CACNA1H) [4].
  • The structure of CACNA1G, the gene encoding alpha1G, a human brain T Ca2+ channel alpha1 subunit, was determined by comparison of polymerase chain reaction-amplified brain cDNA and genomic sequences [3].


  1. Inactivation of CACNA1G, a T-type calcium channel gene, by aberrant methylation of its 5' CpG island in human tumors. Toyota, M., Ho, C., Ohe-Toyota, M., Baylin, S.B., Issa, J.P. Cancer Res. (1999) [Pubmed]
  2. Regulation of alpha1G T-type calcium channel gene (CACNA1G) expression during neuronal differentiation. Bertolesi, G.E., Jollimore, C.A., Shi, C., Elbaum, L., Denovan-Wright, E.M., Barnes, S., Kelly, M.E. Eur. J. Neurosci. (2003) [Pubmed]
  3. Structure and alternative splicing of the gene encoding alpha1G, a human brain T calcium channel alpha1 subunit. Mittman, S., Guo, J., Agnew, W.S. Neurosci. Lett. (1999) [Pubmed]
  4. Molecular characterization of two members of the T-type calcium channel family. Perez-Reyes, E., Lee, J.H., Cribbs, L.L. Ann. N. Y. Acad. Sci. (1999) [Pubmed]
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