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MeSH Review

Calcium Signaling

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Disease relevance of Calcium Signaling


Psychiatry related information on Calcium Signaling


High impact information on Calcium Signaling


Chemical compound and disease context of Calcium Signaling


Biological context of Calcium Signaling


Anatomical context of Calcium Signaling


Associations of Calcium Signaling with chemical compounds


Gene context of Calcium Signaling


Analytical, diagnostic and therapeutic context of Calcium Signaling

  • Altered expression of genes of the Bmp/Smad and Wnt/calcium signaling pathways in the cone-only Nrl-/- mouse retina, revealed by gene profiling using custom cDNA microarrays [36].
  • Our working hypothesis is that disruption of the ontogenetically defined pattern of NMDAR subunit expression and NMDAR-mediated calcium signaling in glutamatergic synapses is a principal mechanism for Pb(2+)-induced deficits in synaptic plasticity and in learning and memory documented in animal models of Pb(2+) neurotoxicity [37].
  • Western blotting of tubule preparations from trp and trpl mutants revealed a correlation between TRPL levels and CAP(2b)-stimulated fluid transport and calcium signaling [38].
  • In the absence of extracellular calcium, perfusion of pancreatic acinar cells with 1 nM CCK-8 and 1 mM vanadate did not significantly affect the typical transient calcium spike induced by CCK-8, but the plateau phase of calcium in response to CCK-8 remained elevated [39].
  • Microinjection of the selective cADPR antagonist 8NH2-cADPR completely abolished subsequent stimulation of Ca2+ signaling via ETA and ETB receptors. cADPR therefore appears to have an obligatory role for ETA-R and ETB-R-mediated calcium signaling in PSMC [40].


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  24. Alpha-haemolysin of uropathogenic E. coli induces Ca2+ oscillations in renal epithelial cells. Uhlén, P., Laestadius, A., Jahnukainen, T., Söderblom, T., Bäckhed, F., Celsi, G., Brismar, H., Normark, S., Aperia, A., Richter-Dahlfors, A. Nature (2000) [Pubmed]
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  26. HSP70 peptide binding mutants separate antigen delivery from dendritic cell stimulation. MacAry, P.A., Javid, B., Floto, R.A., Smith, K.G., Oehlmann, W., Singh, M., Lehner, P.J. Immunity (2004) [Pubmed]
  27. Different nuclear signals are activated by the B cell receptor during positive versus negative signaling. Healy, J.I., Dolmetsch, R.E., Timmerman, L.A., Cyster, J.G., Thomas, M.L., Crabtree, G.R., Lewis, R.S., Goodnow, C.C. Immunity (1997) [Pubmed]
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  30. Ethanol in low doses augments calcium-mediated mechanisms measured intracellularly in hippocampal neurons. Carlen, P.L., Gurevich, N., Durand, D. Science (1982) [Pubmed]
  31. Alteration of stimulus-specific guard cell calcium oscillations and stomatal closing in Arabidopsis det3 mutant. Allen, G.J., Chu, S.P., Schumacher, K., Shimazaki, C.T., Vafeados, D., Kemper, A., Hawke, S.D., Tallman, G., Tsien, R.Y., Harper, J.F., Chory, J., Schroeder, J.I. Science (2000) [Pubmed]
  32. The Albert Lasker Medical Awards. Inositol trisphosphate, calcium, lithium, and cell signaling. Berridge, M.J. JAMA (1989) [Pubmed]
  33. Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1. Tang, T.S., Tu, H., Chan, E.Y., Maximov, A., Wang, Z., Wellington, C.L., Hayden, M.R., Bezprozvanny, I. Neuron (2003) [Pubmed]
  34. Directed selection of MIP-1 alpha neutralizing CCR5 antibodies from a phage display human antibody library. Osbourn, J.K., Earnshaw, J.C., Johnson, K.S., Parmentier, M., Timmermans, V., McCafferty, J. Nat. Biotechnol. (1998) [Pubmed]
  35. Calsenilin reverses presenilin-mediated enhancement of calcium signaling. Leissring, M.A., Yamasaki, T.R., Wasco, W., Buxbaum, J.D., Parker, I., LaFerla, F.M. Proc. Natl. Acad. Sci. U.S.A. (2000) [Pubmed]
  36. Altered expression of genes of the Bmp/Smad and Wnt/calcium signaling pathways in the cone-only Nrl-/- mouse retina, revealed by gene profiling using custom cDNA microarrays. Yu, J., He, S., Friedman, J.S., Akimoto, M., Ghosh, D., Mears, A.J., Hicks, D., Swaroop, A. J. Biol. Chem. (2004) [Pubmed]
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  38. Transient receptor potential-like channels are essential for calcium signaling and fluid transport in a Drosophila epithelium. MacPherson, M.R., Pollock, V.P., Kean, L., Southall, T.D., Giannakou, M.E., Broderick, K.E., Dow, J.A., Hardie, R.C., Davies, S.A. Genetics (2005) [Pubmed]
  39. Vanadate inhibits the calcium extrusion in rat pancreatic acinar cells. Lajas, A.I., Sierra, V., Camello, P.J., Salido, G.M., Pariente, J.A. Cell. Signal. (2001) [Pubmed]
  40. A pivotal role for cADPR-mediated Ca2+ signaling: regulation of endothelin-induced contraction in peritubular smooth muscle cells. Barone, F., Genazzani, A.A., Conti, A., Churchill, G.C., Palombi, F., Ziparo, E., Sorrentino, V., Galione, A., Filippini, A. FASEB J. (2002) [Pubmed]
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