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Gene Review

cra  -  transcriptional repressor-activator for...

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK0081, JW0078, fruC, fruR, shl
 
 
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Disease relevance of fruR

 

High impact information on fruR

 

Biological context of fruR

  • The fruR gene codes for a protein that represses the fru operon and activates the pps gene for PEP synthase [1].
  • The sequence is identical to that of the E. coli shl gene (mnemonic for suppressor-H-linked phenotype) [1].
 

Associations of fruR with chemical compounds

  • In this study we have demonstrated that cra mutant strains synthesize 10-fold less cAMP than isogenic wild-type strains, specifically when grown in fructose-containing minimal media [7].

References

 
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