Disease relevance of chbC

• A single clone encoding the celA and celB genes was identified by screening a T. neapolitana genomic library in Escherichia coli [1].
• The vectors were used to study the expression levels of the Acetobacter xylinum phosphoglucomutase gene celB and the two commonly used reporter genes luc and cat in Escherichia coli, Pseudomonas aeruginosa, and Xanthomonas campestris [2].

High impact information on chbC

• The celA gene encodes a 257-amino-acid protein, while celB encodes a 274-amino-acid protein [1].
• Induced expression levels of luc, cat, and celB from Pm were found to be comparable to or higher than those from the Ptrc and PT7 promoters located on high copy number plasmids [2].

Associations of chbC with chemical compounds

• Northern blots of T. neapolitana mRNA revealed that celA and celB are monocistronic messages, and both genes are inducible by cellobiose and are repressed by glucose [1].

References