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Gene Review:

hisB - histidinol-phosphatase and...

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK2017, JW2004

Fani, R. et al., Chiariotti, L. et al., Basabe, L. et al., Delorme, C. et al.

Basabe, Domínguez, Chávez,

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Disease relevance of hisB

Complementation analysis of three genes, hisA, hisB, and hisG, in Escherichia coli showed that they also were inactive [1].
Cloning of histidine genes of Azospirillum brasilense: organization of the ABFH gene cluster and nucleotide sequence of the hisB gene [2].

High impact information on hisB

Gene structure in the histidine operon of Escherichia coli. Identification and nucleotide sequence of the hisB gene [3].
A DNA fragment, carrying the Candida utilis HIS3 gene, has been isolated from a genomic DNA library by complementation of the E. coli hisB mutant [4].

Chemical compound and disease context of hisB

A significant base sequence homology with the carboxy-terminal moiety of the E. coli hisB gene (0.53) and the Saccharomyces cerevisiae HIS3 gene (0.44), coding for an imidazole glycerolphosphate dehydratase activity was found [2].

Biological context of hisB

In the present study we report the complete nucleotide sequence of the hisB gene of Escherichia coli [3].
The fourth gene of the histidine operon, hisB, was cloned and mapped on a 2,300 base pair DNA fragment [3].

References

Gene inactivation in Lactococcus lactis: histidine biosynthesis. Delorme, C., Godon, J.J., Ehrlich, S.D., Renault, P. J. Bacteriol. (1993) [Pubmed]
Cloning of histidine genes of Azospirillum brasilense: organization of the ABFH gene cluster and nucleotide sequence of the hisB gene. Fani, R., Bazzicalupo, M., Damiani, G., Bianchi, A., Schipani, C., Sgaramella, V., Polsinelli, M. Mol. Gen. Genet. (1989) [Pubmed]
Gene structure in the histidine operon of Escherichia coli. Identification and nucleotide sequence of the hisB gene. Chiariotti, L., Nappo, A.G., Carlomagno, M.S., Bruni, C.B. Mol. Gen. Genet. (1986) [Pubmed]
Cloning and sequence analysis of the Candida utilis HIS3 gene. Basabe, L., Domínguez, I., Chávez, F.P. Biomol. Eng. (2004) [Pubmed]

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