Disease relevance of Nerve Transfer

• A case of giant congenital nevocytic nevus with neurotization and onset of vitiligo [1].
• An increasing number of methods are being developed for the physical therapy and the early repair of the nerve lesions in OBPP, including neuroma excision and nerve grafting, neurolysis and neurotization [2].

High impact information on Nerve Transfer

• Sequestration of VEGF by sVEGFR1 impaired neurotization by approximately 40% (p < .05) [3].
• Motor branches to the pronator teres, flexor pollicis longus, and pronator quadratus muscles were found to be suitable for neurotization of the posterior interosseous nerve at different levels and in various combinations [4].
• In cases in which the C5 or C6 nerve root was available as a donor, neurotization of the supra-scapular nerve was performed with a nerve graft [5].
• Combined nerve transfers for C5 and C6 brachial plexus avulsion injury [6].
• In this direct nerve to muscle neurotization model, the application of AdRSV-BDNF at 3 x 10 (9) pfu/ul did not show enhanced production of BDNF at 1 week [7].

Anatomical context of Nerve Transfer

• Reconstruction of prehension to achieve independent voluntary finger and elbow flexion and extension by the use of double free muscle and multiple nerve transfers following complete avulsion of the brachial plexus (nerve roots C5 to T1) is presented [8].
• Of special interest was the comparison of two commonly applied SSN neurotization procedures: nerve grafting from C5 versus nerve transfer of the accessory nerve [9].
• Intercostal nerves, pectoral nerves, and C4 roots were used for neurotizations, and the sural nerve was used for nerve grafting [10].
• Three patients with avulsed C5, C6, and C7 roots and two patients with avulsed C5 and C6 roots after trauma of the brachial plexus, were treated by neurotization of the biceps using nerve fibers derived from the ulnar nerve and obtained by end-to-side neurorraphy between the ulnar and musculocutaneous nerves [11].

Associations of Nerve Transfer with chemical compounds

• During the 5-year period between 1987 and 1991, 99 patients with total root or upper root (C5, C6, or C7) injuries were treated by nerve transfer to obtain shoulder abduction [12].
• CONCLUSIONS: We recommend combined nerve transfers for C5 and C6 avulsion root injuries [6].
• In cases of preganglionic nerve injury, neurotization from C3, C4 roots was done for reinnervation of trunks or cords [13].
• Hemitongues from the composite group demonstrated formation of new tissue with areas of musclelike tissue extending from islands of residual hydrogel, and we found evidence of neovascularization and possible neurotization [14].

Gene context of Nerve Transfer

• Although neurotization was almost as effective as end-to-end nerve repair for reinnervating muscle, LIF had no increased effect on neurotization [15].

References