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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Accessory Nerve

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Disease relevance of Accessory Nerve


High impact information on Accessory Nerve


Biological context of Accessory Nerve

  • Consistent with this phenotype, immature branchial motoneurons of the spinal accessory nerve, which normally migrate from a ventromedial to a dorsolateral position within the neural tube, were markedly reduced in Nkx2.9-deficient embryos at E10.5, while ventromedial motor column cells were increased in numbers [2].

Anatomical context of Accessory Nerve


Associations of Accessory Nerve with chemical compounds

  • Motoneurons of the spinal accessory nerve between C1 and C5 segments were labelled using wheat germ agglutinin-horseradish peroxidase (WGA-HRP) injected into the sternocleidomastoid muscles [11].
  • The dorsal C2 and C3 branches have diameters comparable to that of the spinal accessory nerve [12].
  • Reconstruction of the spinal accessory nerve with an anastomosis to the dorsal C3 branch: technical note [12].
  • Motoneurons supplying the accessory nerve (nXI) of the Japanese toad were retrogradely labelled by applying the cobaltic lysine to the cut end of the nerve [13].
  • Retrograde transport of the fluorescent tracers Diamidino Yellow dihydrochloride and Fast Blue was used to determine the location of the spinal nucleus of the accessory nerve in the sheep [14].

Gene context of Accessory Nerve


Analytical, diagnostic and therapeutic context of Accessory Nerve


  1. Tumor above the spinal accessory nerve in papillary thyroid cancer that involves lateral neck nodes: a common occurrence. Pingpank, J.F., Sasson, A.R., Hanlon, A.L., Friedman, C.D., Ridge, J.A. Arch. Otolaryngol. Head Neck Surg. (2002) [Pubmed]
  2. Targeted disruption of the homeobox gene Nkx2.9 reveals a role in development of the spinal accessory nerve. Pabst, O., Rummelies, J., Winter, B., Arnold, H.H. Development (2003) [Pubmed]
  3. Neuromuscular function and plasma drug levels in pyridostigmine treatment of myasthenia gravis. Breyer-Pfaff, U., Schmezer, A., Maier, U., Brinkmann, A., Schumm, F. J. Neurol. Neurosurg. Psychiatr. (1990) [Pubmed]
  4. Persistent abnormal shoulder elevation after accessory nerve injury and differential diagnosis with post-traumatic focal shoulder-elevation dystonia: report of a case and literature review. Cossu, G., Melis, M., Melis, G., Ferrigno, P., Molari, A. Mov. Disord. (2004) [Pubmed]
  5. Sternomastoid function during hemispheric suppression by amytal: insights into the inputs to the spinal accessory nerve nucleus. DeToledo, J.C., Dow, R. Mov. Disord. (1998) [Pubmed]
  6. Localization of the spinal accessory motoneurons in the cervical cord in connection with the phrenic nucleus: an HRP study in cats. Satomi, H., Takahashi, K., Aoki, M., Kasaba, T., Kurosawa, Y., Otsuka, K. Brain Res. (1985) [Pubmed]
  7. Level IIb lymph node metastasis in laryngeal squamous cell carcinoma. Lim, Y.C., Lee, J.S., Koo, B.S., Choi, E.C. Laryngoscope (2006) [Pubmed]
  8. Motor innervation of the trapezius muscle: a histochemical study. Karuman, P.M., Soo, K.C. Head & neck. (1996) [Pubmed]
  9. Isolation and characterization of axolemma-enriched fractions from rabbit and bovine peripheral nerve. Yoshino, J.E., DeVries, G.H. Neurochem. Res. (1993) [Pubmed]
  10. Accessory nerve neurotization in infants with brachial plexus birth palsy. Kawabata, H., Kawai, H., Masatomi, T., Yasui, N. Microsurgery. (1994) [Pubmed]
  11. Three-dimensional topographic analysis of spinal accessory motoneurons under chronic mechanical compression: an experimental study in the mouse. Baba, H., Maezawa, Y., Uchida, K., Imura, S., Kawahara, N., Tomita, K., Kudo, M. J. Neurol. (1997) [Pubmed]
  12. Reconstruction of the spinal accessory nerve with an anastomosis to the dorsal C3 branch: technical note. Braun, V., Mayer, M., Antoniadis, G., Richter, H.P., Schröder, J.M. Neurosurgery (1996) [Pubmed]
  13. Morphology and distribution of the motor neurons of the accessory nerve (nXI) in the Japanese toad: a cobaltic lysine study. Oka, Y., Satou, M., Ueda, K. Brain Res. (1987) [Pubmed]
  14. Motoneuron organisation of the muscles of the spinal accessory complex of the sheep investigated with the fluorescent retrograde tracer technique. Clavenzani, P., Scapolo, P.A., Callegari, E., Barazzoni, A.M., Petrosino, G., Lucchi, M.L., Bortolami, R. J. Anat. (1994) [Pubmed]
  15. Peroperative diagnosis and treatment of metastases to the regional lymph nodes in papillary carcinoma of the thyroid gland. Hamming, J.F., van de Velde, C.J., Goslings, B.M., Fleuren, G.J., Hermans, J., Delemarre, J.F., van Slooten, E.A. Surgery, gynecology & obstetrics. (1989) [Pubmed]
  16. Vulnerability of the spinal accessory nerve in the posterior triangle of the neck: a cadaveric study. Lu, L., Haman, S.P., Ebraheim, N.A. Orthopedics. (2002) [Pubmed]
  17. Molecular assessment of neck dissections supports preserving level IIB lymph nodes in selective neck dissection for laryngeal squamous cell carcinoma with a clinically negative neck. Elsheikh, M.N., Mahfouz, M.E., Salim, E.I., Elsheikh, E.A. ORL J. Otorhinolaryngol. Relat. Spec. (2006) [Pubmed]
  18. External rotation as a result of suprascapular nerve neurotization in obstetric brachial plexus lesions. Pondaag, W., de Boer, R., van Wijlen-Hempel, M.S., Hofstede-Buitenhuis, S.M., Malessy, M.J. Neurosurgery (2005) [Pubmed]
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