Disease relevance of Hemorrhagic Disease Virus, Rabbit

• The rabbit hemorrhagic disease virus capsid protein was expressed in insect cells either as an individual protein species, from a mRNA analogous to the viral subgenomic RNA, or as part of a polyprotein that included the viral 3C-like protease and the RNA polymerase [1].
• The cleavage map of SaV ORF1 is similar to those of other heretofore known members of the family Caliciviridae, especially to rabbit hemorrhagic disease virus, a member of the genus Lagovirus [2].

High impact information on Hemorrhagic Disease Virus, Rabbit

• Binding of rabbit hemorrhagic disease virus to antigens of the ABH histo-blood group family [3].
• ATP binding and ATPase activities associated with recombinant rabbit hemorrhagic disease virus 2C-like polypeptide [4].
• Gene transfer using recombinant rabbit hemorrhagic disease virus capsids with genetically modified DNA encapsidation capacity by addition of packaging sequences from the L1 or L2 protein of human papillomavirus type 16 [5].
• Processing of rabbit hemorrhagic disease virus polyprotein [6].
• Our data show that rabbit hemorrhagic disease virus encodes a trypsin-like cysteine protease that is similar to 3C proteases with regard to function and specificity but is more similar to 2A proteases with regard to size [7].

Chemical compound and disease context of Hemorrhagic Disease Virus, Rabbit

• Detection of rabbit haemorrhagic disease virus (RHDV) by in situ hybridisation with a digoxigenin labelled RNA probe [8].
• Formalin fixed liver, spleen, kidney, heart, lung, duodenum and appendix tissues from nine rabbits, experimentally infected with rabbit haemorrhagic disease virus (RHDV), were investigated for evidence of RHDV antigen by the direct avidin-biotin peroxidase complex immunohistochemical method [9].

Anatomical context of Hemorrhagic Disease Virus, Rabbit

• The ability of rabbit hemorrhagic disease virus to agglutinate human erythrocytes and to attach to rabbit epithelial cells of the upper respiratory and digestive tracts was shown to depend on the presence of ABH blood group antigens [3].

Gene context of Hemorrhagic Disease Virus, Rabbit

• 3C-like protease of rabbit hemorrhagic disease virus: identification of cleavage sites in the ORF1 polyprotein and analysis of cleavage specificity [7].
• Partial characterization of the human erythrocyte receptor for rabbit haemorrhagic disease virus [10].

References