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MeSH Review:

Conjunctivitis, Inclusion

Rank, R.G. et al., Sayada, C. et al., Coles, A.M. et al., Katusic, D. et al., Rank, R.G. et al., et al.

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Disease relevance of Conjunctivitis, Inclusion

METHODS: Guinea pigs were immunized either subcutaneously with recombinant Hsp60 or both subcutaneously with recombinant Hsp60 and ocularly with attenuated Salmonella typhimurium expressing the guinea pig inclusion conjunctivitis (GPIC) Hsp60 antigen [1].
The effect of omission of individual amino acids from growth medium on the multiplication of Chlamydia psittaci (strain guinea pig inclusion conjunctivitis) in cycloheximide-treated McCoy cells has been examined [2].

High impact information on Conjunctivitis, Inclusion

Treatment with estradiol was found to markedly influence the course of genital infection with the chlamydial agent of guinea pig inclusion conjunctivitis, producing infections of greater intensity and longer duration than those in control animals [3].
Female guinea pigs infected in the genital tract with the chlamydial agent of guinea pig inclusion conjunctivitis were selectively immunosuppressed by varying regimens of cyclophosphamide (Cy) treatment [4].
Persistence of inclusion conjunctivitis after oral erythromycin therapy [5].
Conversely, infection with MoPn (C. muridarum) but not LGV/L2 led to BAX activation after 72 h, as previously reported for shorter (48 h) infection with the guinea pig inclusion conjunctivitis (GPIC) serovar of C. psittaci (C. caviae) [6].
Azithromycin vs doxycycline in the treatment of inclusion conjunctivitis [7].

Chemical compound and disease context of Conjunctivitis, Inclusion

Treatment with 100 mg of Cy per kg at 9-day intervals resulted in an extended infection which resolved concomitantly with the development of antibody to guinea pig inclusion conjunctivitis [4].
CONCLUSIONS: A single 1-g azithromycin therapy was as effective as standard 10-day treatment with doxycycline (100 mg twice daily) in the treatment of adult inclusion conjunctivitis [7].
Using the Chlamydia psittaci strain guinea pig inclusion conjunctivitis (GPIC), in the presence of cycloheximide, the requirement for valine was abrogated by the simultaneous omission of isoleucine, that for phenylalanine by simultaneous omission of tryptophan and that for leucine by simultaneous omission of isoleucine plus valine [8].

Biological context of Conjunctivitis, Inclusion

Serotyping of Chlamydia trachomatis from inclusion conjunctivitis by polymerase chain reaction and restriction fragment length polymorphism analysis [9].

Analytical, diagnostic and therapeutic context of Conjunctivitis, Inclusion

Thirteen feline Chlamydia psittaci strains isolated in various countries over a 50-year period were examined by restriction mapping of the major outer membrane protein (MOMP) gene obtained after DNA amplification by the polymerase chain reaction and compared with avian, ovine and guinea pig inclusion conjunctivitis (GPIC) C psittaci strains [10].

References

Systemic immunization with Hsp60 alters the development of chlamydial ocular disease. Rank, R.G., Dascher, C., Bowlin, A.K., Bavoil, P.M. Invest. Ophthalmol. Vis. Sci. (1995) [Pubmed]
Differential amino acid utilization by Chlamydia psittaci (strain guinea pig inclusion conjunctivitis) and its regulatory effect on chlamydial growth. Allan, I., Pearce, J.H. J. Gen. Microbiol. (1983) [Pubmed]
Effect of estradiol on chlamydial genital infection of female guinea pigs. Rank, R.G., White, H.J., Hough, A.J., Pasley, J.N., Barron, A.L. Infect. Immun. (1982) [Pubmed]
Humoral immunity in the resolution of genital infection in female guinea pigs infected with the agent of guinea pig inclusion conjunctivitis. Rank, R.G., White, H.J., Barron, A.L. Infect. Immun. (1979) [Pubmed]
Persistence of inclusion conjunctivitis after oral erythromycin therapy. Laperrière, H., Lefebvre, J. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne. (1988) [Pubmed]
Cell death, BAX activation, and HMGB1 release during infection with Chlamydia. Jungas, T., Verbeke, P., Darville, T., Ojcius, D.M. Microbes Infect. (2004) [Pubmed]
Azithromycin vs doxycycline in the treatment of inclusion conjunctivitis. Katusic, D., Petricek, I., Mandic, Z., Petric, I., Salopek-Rabatic, J., Kruzic, V., Oreskovic, K., Sikic, J., Petricek, G. Am. J. Ophthalmol. (2003) [Pubmed]
Regulation of Chlamydia psittaci (strain guinea pig inclusion conjunctivitis) growth in McCoy cells by amino acid antagonism. Coles, A.M., Pearce, J.H. J. Gen. Microbiol. (1987) [Pubmed]
Serotyping of Chlamydia trachomatis from inclusion conjunctivitis by polymerase chain reaction and restriction fragment length polymorphism analysis. Isobe, K., Aoki, K., Itoh, N., Ohno, S., Takashima, I., Hashimoto, N. Jpn. J. Ophthalmol. (1996) [Pubmed]
Homogeneity of the major outer membrane protein gene of feline Chlamydia psittaci. Sayada, C., Andersen, A., Rodriguez, P., Eb, F., Milon, A., Elion, J., Denamur, E. Res. Vet. Sci. (1994) [Pubmed]

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