Disease relevance of Pars Planitis

• PURPOSE: To identify the ocular complications and to statistically evaluate the possible association of pars planitis with multiple sclerosis (MS) in a homogeneous population of pars planitis patients [1].
• One patient had a history of myotonic muscular dystrophy, another had pars planitis, and the third had high myopia [2].
• METHODS: A 44-year-old man with asymmetrical pars planitis complicated by right cystoid macular edema was treated with multiple right orbital floor injections of triamcinolone through the lower eyelid [3].
• PURPOSE: To determine the levels of interleukin-1 receptor antagonist (IL-1ra) in the blood serum of patients with idiopathic bilateral pars planitis and Behçet disease [4].
• PURPOSE: To characterize the extracellular matrix and cellular components of a 'snowbank' removed during vitreous surgery for treatment of retinal detachment complicating pars planitis [5].

High impact information on Pars Planitis

• Patients with active pars planitis have increased levels of a 36 kDa protein (p-36) in their circulation [6].
• The authors report the first study of patients with refractory pars planitis in which fluorescein angiography of the inferior pars plana snowbanks was performed both before and after cryopexy of the vitreous base [7].
• BACKGROUND: Transconjunctival cryopexy of the vitreous base is clinically effective in patients with steroid nonresponsive pars planitis who have peripheral neovascularization [7].
• Exclusion of five patients with pars planitis in whom MS subsequently developed did not change the significance of these findings [8].
• Ciclosporin (Sandimmun) therapy: experience in the treatment of pars planitis and present therapeutic guidelines [9].

Biological context of Pars Planitis

• The 36 kDa protein (p-36) detected at increased levels in the blood of patients with active pars planitis was cloned from a human spleen cDNA library [6].

References