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MeSH Review

Pars Planitis

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Disease relevance of Pars Planitis


High impact information on Pars Planitis

  • Patients with active pars planitis have increased levels of a 36 kDa protein (p-36) in their circulation [6].
  • The authors report the first study of patients with refractory pars planitis in which fluorescein angiography of the inferior pars plana snowbanks was performed both before and after cryopexy of the vitreous base [7].
  • BACKGROUND: Transconjunctival cryopexy of the vitreous base is clinically effective in patients with steroid nonresponsive pars planitis who have peripheral neovascularization [7].
  • Exclusion of five patients with pars planitis in whom MS subsequently developed did not change the significance of these findings [8].
  • Ciclosporin (Sandimmun) therapy: experience in the treatment of pars planitis and present therapeutic guidelines [9].

Biological context of Pars Planitis

  • The 36 kDa protein (p-36) detected at increased levels in the blood of patients with active pars planitis was cloned from a human spleen cDNA library [6].


  1. Long-term visual outcome and complications associated with pars planitis. Malinowski, S.M., Pulido, J.S., Folk, J.C. Ophthalmology (1993) [Pubmed]
  2. Progressive constriction of the anterior capsular opening following intact capsulorhexis. Hansen, S.O., Crandall, A.S., Olson, R.J. Journal of cataract and refractive surgery. (1993) [Pubmed]
  3. Lower eyelid herniation of orbital fat may complicate periocular corticosteroid injection. Smith, J.R., George, R.K., Rosenbaum, J.T. Am. J. Ophthalmol. (2002) [Pubmed]
  4. Blood serum interleukin-1 receptor antagonist in pars planitis and ocular Behçet disease. Benezra, D., Maftzir, G., Barak, V. Am. J. Ophthalmol. (1997) [Pubmed]
  5. An immunohistochemical study of the 'snowbank' in a case of pars planiti. Abu El-Asrar, A.M., Geboes, K. Ocul. Immunol. Inflamm. (2002) [Pubmed]
  6. Molecular cloning, sequencing, and expression of the 36 kDa protein present in pars planitis. Sequence homology with yeast nucleopore complex protein. Bora, N.S., Bora, P.S., Tandhasetti, M.T., Cirrito, T.P., Kaplan, H.J. Invest. Ophthalmol. Vis. Sci. (1996) [Pubmed]
  7. A fluorescein angiographic study of patients with pars planitis and peripheral exudation (snowbanking) before and after cryopexy. Josephberg, R.G., Kanter, E.D., Jaffee, R.M. Ophthalmology (1994) [Pubmed]
  8. The association of HLA-B8, B51, DR2, and multiple sclerosis in pars planitis. Malinowski, S.M., Pulido, J.S., Goeken, N.E., Brown, C.K., Folk, J.C. Ophthalmology (1993) [Pubmed]
  9. Ciclosporin (Sandimmun) therapy: experience in the treatment of pars planitis and present therapeutic guidelines. Nussenblatt, R.B., Palestine, A.G. Developments in ophthalmology. (1992) [Pubmed]
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