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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Retinal Detachment

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Disease relevance of Retinal Detachment


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Chemical compound and disease context of Retinal Detachment


Biological context of Retinal Detachment


Anatomical context of Retinal Detachment


Gene context of Retinal Detachment


Analytical, diagnostic and therapeutic context of Retinal Detachment


  1. Variation in the vitreous phenotype of Stickler syndrome can be caused by different amino acid substitutions in the X position of the type II collagen Gly-X-Y triple helix. Richards, A.J., Baguley, D.M., Yates, J.R., Lane, C., Nicol, M., Harper, P.S., Scott, J.D., Snead, M.P. Am. J. Hum. Genet. (2000) [Pubmed]
  2. Molecular analysis of the genetic defect in a large cohort of IP patients and identification of novel NEMO mutations interfering with NF-kappaB activation. Fusco, F., Bardaro, T., Fimiani, G., Mercadante, V., Miano, M.G., Falco, G., Israël, A., Courtois, G., D'Urso, M., Ursini, M.V. Hum. Mol. Genet. (2004) [Pubmed]
  3. Retinal vascular abnormalities in facioscapulohumeral muscular dystrophy. A general association with genetic and therapeutic implications. Fitzsimons, R.B., Gurwin, E.B., Bird, A.C. Brain (1987) [Pubmed]
  4. PCR assay confirms diagnosis in syndrome with variably expressed phenotype: mutation detection in Stickler syndrome. Ahmad, N.N., McDonald-McGinn, D.M., Dixon, P., Zackai, E.H., Tasman, W.S. J. Med. Genet. (1996) [Pubmed]
  5. High TGF-beta2 levels during primary retinal detachment may protect against proliferative vitreoretinopathy. Dieudonné, S.C., La Heij, E.C., Diederen, R., Kessels, A.G., Liem, A.T., Kijlstra, A., Hendrikse, F. Invest. Ophthalmol. Vis. Sci. (2004) [Pubmed]
  6. Peripheral proliferative retinopathies. Brown, G.C., Brown, R.H., Brown, M.M. International ophthalmology. (1987) [Pubmed]
  7. Increased ocular levels of IGF-1 in transgenic mice lead to diabetes-like eye disease. Ruberte, J., Ayuso, E., Navarro, M., Carretero, A., Nacher, V., Haurigot, V., George, M., Llombart, C., Casellas, A., Costa, C., Bosch, A., Bosch, F. J. Clin. Invest. (2004) [Pubmed]
  8. Correlation of fibrosis and transforming growth factor-beta type 2 levels in the eye. Connor, T.B., Roberts, A.B., Sporn, M.B., Danielpour, D., Dart, L.L., Michels, R.G., de Bustros, S., Enger, C., Kato, H., Lansing, M. J. Clin. Invest. (1989) [Pubmed]
  9. Dystrophin in the retina. Schmitz, F., Drenckhahn, D. Prog. Neurobiol. (1997) [Pubmed]
  10. Inducible expression of vascular endothelial growth factor in adult mice causes severe proliferative retinopathy and retinal detachment. Ohno-Matsui, K., Hirose, A., Yamamoto, S., Saikia, J., Okamoto, N., Gehlbach, P., Duh, E.J., Hackett, S., Chang, M., Bok, D., Zack, D.J., Campochiaro, P.A. Am. J. Pathol. (2002) [Pubmed]
  11. Photoreceptor-specific expression of platelet-derived growth factor-B results in traction retinal detachment. Seo, M.S., Okamoto, N., Vinores, M.A., Vinores, S.A., Hackett, S.F., Yamada, H., Yamada, E., Derevjanik, N.L., LaRochelle, W., Zack, D.J., Campochiaro, P.A. Am. J. Pathol. (2000) [Pubmed]
  12. Oxidative retinal products and ocular damages in diabetic patients. Grattagliano, I., Vendemiale, G., Boscia, F., Micelli-Ferrari, T., Cardia, L., Altomare, E. Free Radic. Biol. Med. (1998) [Pubmed]
  13. Early glial cell reactivity in experimental retinal detachment: effect of suramin. Uhlmann, S., Bringmann, A., Uckermann, O., Pannicke, T., Weick, M., Ulbricht, E., Goczalik, I., Reichenbach, A., Wiedemann, P., Francke, M. Invest. Ophthalmol. Vis. Sci. (2003) [Pubmed]
  14. Intravitreal ganciclovir concentration after intravenous administration in AIDS patients with cytomegalovirus retinitis: implications for therapy. Kuppermann, B.D., Quiceno, J.I., Flores-Aguilar, M., Connor, J.D., Capparelli, E.V., Sherwood, C.H., Freeman, W.R. J. Infect. Dis. (1993) [Pubmed]
  15. The effect of combined daunorubicin and triamcinolone acetonide treatment on a refined experimental model of proliferative vitreoretinopathy. Chen, E.P., Steinhorst, U.H., Samsa, G.P., Saloupis, P.T., Hatchell, D.L. Invest. Ophthalmol. Vis. Sci. (1992) [Pubmed]
  16. Immunocytochemical localization of glutamate in normal and detached cat retina. Sasoh, M., Ma, N., Yoshida, S., Semba, R., Uji, Y. Invest. Ophthalmol. Vis. Sci. (1998) [Pubmed]
  17. Caspase activation in an experimental model of retinal detachment. Zacks, D.N., Hänninen, V., Pantcheva, M., Ezra, E., Grosskreutz, C., Miller, J.W. Invest. Ophthalmol. Vis. Sci. (2003) [Pubmed]
  18. Rapid glutamatergic alterations in the neural retina induced by retinal detachment. Sherry, D.M., Townes-Anderson, E. Invest. Ophthalmol. Vis. Sci. (2000) [Pubmed]
  19. Facilitation of artificial retinal detachment for macular translocation surgery tested in rabbit. Faude, F., Wendt, S., Biedermann, B., Gärtner, U., Kacza, J., Seeger, J., Reichenbach, A., Wiedemann, P. Invest. Ophthalmol. Vis. Sci. (2001) [Pubmed]
  20. Vascular adhesion molecules in vitreous from eyes with proliferative diabetic retinopathy. Limb, G.A., Hickman-Casey, J., Hollifield, R.D., Chignell, A.H. Invest. Ophthalmol. Vis. Sci. (1999) [Pubmed]
  21. Outcomes and complications associated with perfluoro-n-octane and perfluoroperhydrophenanthrene in complex retinal detachment repair. Scott, I.U., Murray, T.G., Flynn, H.W., Smiddy, W.E., Feuer, W.J., Schiffman, J.C. Ophthalmology (2000) [Pubmed]
  22. Macrophages and dendritic cells in IRBP-induced experimental autoimmune uveoretinitis in B10RIII mice. Jiang, H.R., Lumsden, L., Forrester, J.V. Invest. Ophthalmol. Vis. Sci. (1999) [Pubmed]
  23. FGFR1, signaling, and AP-1 expression after retinal detachment: reactive Müller and RPE cells. Geller, S.F., Lewis, G.P., Fisher, S.K. Invest. Ophthalmol. Vis. Sci. (2001) [Pubmed]
  24. Ocular and scleral alterations in gene-targeted lumican-fibromodulin double-null mice. Chakravarti, S., Paul, J., Roberts, L., Chervoneva, I., Oldberg, A., Birk, D.E. Invest. Ophthalmol. Vis. Sci. (2003) [Pubmed]
  25. Cytokines and serum cause alpha 2 beta 1 integrin-mediated contraction of collagen gels by cultured retinal pigment epithelial cells. Hunt, R.C., Pakalnis, V.A., Choudhury, P., Black, E.P. Invest. Ophthalmol. Vis. Sci. (1994) [Pubmed]
  26. A novel mutation of COL2A1 resulting in dominantly inherited rhegmatogenous retinal detachment. Richards, A.J., Meredith, S., Poulson, A., Bearcroft, P., Crossland, G., Baguley, D.M., Scott, J.D., Snead, M.P. Invest. Ophthalmol. Vis. Sci. (2005) [Pubmed]
  27. Refined genetic and physical localization of the Wagner disease (WGN1) locus and the genes CRTL1 and CSPG2 to a 2- to 2.5-cM region of chromosome 5q14.3. Perveen, R., Hart-Holden, N., Dixon, M.J., Wiszniewski, W., Fryer, A.E., Brunner, H.G., Pinkners, A.J., van Beersum, S.E., Black, G.C. Genomics (1999) [Pubmed]
  28. Diabetic patients and retinal proliferation: an evaluation of the role of vascular endothelial growth factor (VEGF). Nicoletti, V.G., Nicoletti, R., Ferrara, N., Meli, G., Reibaldi, M., Reibaldi, A. Exp. Clin. Endocrinol. Diabetes (2003) [Pubmed]
  29. Phosphorylation of extracellular signal-regulated kinase and p27(KIP1) after retinal detachment. Kase, S., Yoshida, K., Harada, T., Harada, C., Namekata, K., Suzuki, Y., Ohgami, K., Shiratori, K., Nakayama, K.I., Ohno, S. Graefes Arch. Clin. Exp. Ophthalmol. (2006) [Pubmed]
  30. Biodegradable microspheres containing adriamycin in the treatment of proliferative vitreoretinopathy. Moritera, T., Ogura, Y., Yoshimura, N., Honda, Y., Wada, R., Hyon, S.H., Ikada, Y. Invest. Ophthalmol. Vis. Sci. (1992) [Pubmed]
  31. Rapid upregulation of fibroblast growth factor receptor 1 (flg) by rat photoreceptor cells after injury. Ozaki, S., Radeke, M.J., Anderson, D.H. Invest. Ophthalmol. Vis. Sci. (2000) [Pubmed]
  32. Massive mycobacterial choroiditis during highly active antiretroviral therapy: another immune-recovery uveitis? Zamir, E., Hudson, H., Ober, R.R., Kumar, S.K., Wang, R.C., Read, R.W., Rao, N.A. Ophthalmology (2002) [Pubmed]
  33. Retrobulbar bupivacaine irrigation for postoperative pain after scleral buckling surgery. A prospective study. Duker, J.S., Nielsen, J., Vander, J.F., Rosenstein, R.B., Benson, W.E. Ophthalmology (1991) [Pubmed]
  34. Long-term follow-up of retinal detachment due to macular hole in myopic eyes treated by temporary silicone oil tamponade and laser photocoagulation. Wolfensberger, T.J., Gonvers, M. Ophthalmology (1999) [Pubmed]
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