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High impact information on Crepis

  • The mechanism by which the fatty acid acetylenase of Crepis alpina catalyzes crepenynic acid ((9Z)-octadeca-9-en-12-ynoic acid) production from linoleic acid has been probed through the use of kinetic isotope effect (KIE) measurements [1].
  • The Crepis palaestina cDNA Cpal2 encodes a delta 12-epoxygenase that can catalyse the synthesis of 12,13-epoxy-cis-9-octadecenoic acid (18:1E) from linoleic acid (18:2) [2].
  • Arabidopsis thaliana (L.) Heynh. expressing the Crepis palaestina (L.) linoleic acid delta12-epoxygenase in its developing seeds typically accumulates low levels of vernolic acid (12,13-epoxy-octadec-cis-9-enoic acid) in comparison to levels found in seeds of the native C. palaestina [3].
  • The evolutionarily closely related Delta12 epoxygenase from Crepis palaestina had only weak desaturase activity but could also produce 9(Z),12(E)-octadecadienoate from oleate [4].
  • From the roots of Crepis mollis, one new and two known guaianolides were isolated together with eight known guaianolide glycosides, one known germacranolide glycoside and two known phenylpropanoids [5].

Biological context of Crepis


Associations of Crepis with chemical compounds


  1. Mechanistic study of an improbable reaction: alkene dehydrogenation by the delta12 acetylenase of Crepis alpina. Reed, D.W., Polichuk, D.R., Buist, P.H., Ambrose, S.J., Sasata, R.J., Savile, C.K., Ross, A.R., Covello, P.S. J. Am. Chem. Soc. (2003) [Pubmed]
  2. Transgenic expression of a delta 12-epoxygenase gene in Arabidopsis seeds inhibits accumulation of linoleic acid. Singh, S., Thomaeus, S., Lee, M., Stymne, S., Green, A. Planta (2001) [Pubmed]
  3. Level of accumulation of epoxy fatty acid in Arabidopsis thaliana expressing a linoleic acid delta12-epoxygenase is influenced by the availability of the substrate linoleic acid. Rezzonico, E., Moire, L., Delessert, S., Poirier, Y. Theor. Appl. Genet. (2004) [Pubmed]
  4. Properties of two multifunctional plant fatty acid acetylenase/desaturase enzymes. Carlsson, A.S., Thomaeus, S., Hamberg, M., Stymne, S. Eur. J. Biochem. (2004) [Pubmed]
  5. Sesquiterpenoids and phenolics from Crepis mollis. Kisie, W., Zielińska, K., Joshi, S.P. Phytochemistry (2000) [Pubmed]
  6. Purine receptor agonists protect the genome of plant and animal cells from clastogen damage. Kharitonov, V.S., Semenov, V.V., Barabanshchikov, B.I. Bull. Exp. Biol. Med. (2001) [Pubmed]
  7. The involvement of phospholipid:diacylglycerol acyltransferases in triacylglycerol production. Banaś, A., Dahlqvist, A., Ståhl, U., Lenman, M., Stymne, S. Biochem. Soc. Trans. (2000) [Pubmed]
  8. A germacranolide and three hydroxybenzyl alcohol derivatives from Hieracium murorum and Crepis bocconi. Zidorn, C., Ellmerer-Müller, E.P., Stuppner, H. Phytochemical analysis : PCA. (2001) [Pubmed]
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