Chemical Compound Review:
Isopropylphenyladenosine (2R,3S,4R,5R)-2- (hydroxymethyl)-5-[6...
Synonyms:
AC1L1RPC, PHENYLISOPROPYLADENOSINE, N6-(Phenylisopropyl)-adenosine, Adenosine, N-(1-methylethyl)-N-phenyl-
- Pertussis toxin reverses adenosine inhibition of neuronal glutamate release. Dolphin, A.C., Prestwich, S.A. Nature (1985)
- Inhibition of adenylate cyclase in rat brain synaptosomal membranes by GTP and phenylisopropyladenosine is enhanced in hypothyroidism. Mazurkiewicz, D., Saggerson, E.D. Biochem. J. (1989)
- Endogenous adenosine reduces depression of cardiac function induced by beta-adrenergic stimulation during low flow perfusion. Fenton, R.A., Galeckas, K.J., Dobson, J.G. J. Mol. Cell. Cardiol. (1995)
- Quinolinic acid neurotoxicity: protection by intracerebral phenylisopropyladenosine (PIA) and potentiation by hypotension. Connick, J.H., Stone, T.W. Neurosci. Lett. (1989)
- Hormone-sensitive cyclic GMP-inhibited cyclic AMP phosphodiesterase in rat adipocytes. Regulation of insulin- and cAMP-dependent activation by phosphorylation. Smith, C.J., Vasta, V., Degerman, E., Belfrage, P., Manganiello, V.C. J. Biol. Chem. (1991)
- Resistance to insulin-stimulated glucose uptake in adipocytes isolated from spontaneously hypertensive rats. Reaven, G.M., Chang, H., Hoffman, B.B., Azhar, S. Diabetes (1989)
- Insulin antagonism of catecholamine stimulation of fatty acid transport in the adipocyte. Studies on its mechanism of action. Abumrad, N.A., Harmon, C.M., Barnela, U.S., Whitesell, R.R. J. Biol. Chem. (1988)
- Presence of a functional inhibitory GTP-binding regulatory component, Gi, linked to adenylate cyclase in adipocytes of ob/ob mice. Greenberg, A.S., Taylor, S.I., Londos, C. J. Biol. Chem. (1987)
- Regulation of insulin-stimulated glucose transport in the isolated rat adipocyte. cAMP-independent effects of lipolytic and antilipolytic agents. Kuroda, M., Honnor, R.C., Cushman, S.W., Londos, C., Simpson, I.A. J. Biol. Chem. (1987)
- Adenosine inhibition of the hormonal response in the Sertoli cell is reversed by pertussis toxin. Monaco, L., DeManno, D.A., Martin, M.W., Conti, M. Endocrinology (1988)
- Changes in the anti-lipolytic action and binding to plasma membranes of N6-L-phenylisopropyladenosine in adipocytes from starved and hypothyroid rats. Chohan, P., Carpenter, C., Saggerson, E.D. Biochem. J. (1984)
- P2-purinergic activation of phosphoinositide turnover is potentiated by A1-receptor stimulation in thyroid cells. Nazarea, M., Okajima, F., Kondo, Y. Eur. J. Pharmacol. (1991)
- Duality in the mastoparan action on glucose transport in rat adipocytes. Omata, W., Suzuki, Y., Kojima, I., Shibata, H. Endocr. J. (2005)
- Influence of development and reduction of fat stores on the antilipolytic alpha 2-adrenoceptor in hamster adipocytes: comparison with adenosine and beta-adrenergic lipolytic responses. Carpene, C., Berlan, M., Lafontan, M. J. Lipid Res. (1983)
- The adenosine Ri agonist, phenylisopropyladenosine, reduces high affinity isoproterenol binding to the beta-adrenergic receptor of rat myocardial membranes. Romano, F.D., Fenton, R.A., Dobson, J.G. Second Messengers Phosphoproteins (1988)
- Diabetes decreases sensitivity of adipocyte lipolysis to inhibition by Gi-linked receptor agonists. Saggerson, D., Orford, M., Chatzipanteli, K., Shepherd, J. Cell. Signal. (1991)
- Regulation of lipolysis by somatotropin: functional alteration of adrenergic and adenosine signaling in bovine adipose tissue. Houseknecht, K.L., Bauman, D.E. J. Endocrinol. (1997)
- Regulation of hormone-receptor coupling to adenylyl cyclase. Effects of GTP and GDP. Iyengar, R., Abramowitz, J., Bordelon-Riser, M., Blume, A.J., Birnbaumer, L. J. Biol. Chem. (1980)
- Growth hormone decreases the response to anti-lipolytic agonists and decreases the levels of Gi2 in rat adipocytes. Doris, R., Vernon, R.G., Houslay, M.D., Kilgour, E. Biochem. J. (1994)
- Enhanced negative inotropic effect of an adenosine A1-receptor agonist in rat left atria in hypothyroidism. Kaasik, A., Seppet, E.K., Ohisalo, J.J. J. Mol. Cell. Cardiol. (1994)
- Dietary fat saturation and endurance exercise alter lipolytic sensitivity of adipocytes isolated from Yucatan miniature swine. Meservey, C.M., Carey, G.B. J. Nutr. (1994)
- Lack of apparent receptor reserve at postsynaptic 5-hydroxytryptamine1A receptors negatively coupled to adenylyl cyclase activity in rat hippocampal membranes. Yocca, F.D., Iben, L., Meller, E. Mol. Pharmacol. (1992)
- Receptor cross-talk can optimize assays for autoantibodies to the thyrotropin receptor: effect of phenylisopropyladenosine on adenosine 3',5'-monophosphate and inositol phosphate levels in rat FRTL-5 thyroid cells. Hidaka, A., Okajima, F., Ban, T., Kosugi, S., Kondo, Y., Kohn, L.D. J. Clin. Endocrinol. Metab. (1993)
- Dual regulation by cAMP of beta-hexosaminidase-induced mitogenesis in bovine tracheal myocytes. Lew, D.B., Nebigil, C., Malik, K.U. Am. J. Respir. Cell Mol. Biol. (1992)
- In vivo effects of interferon-alpha and interferon-gamma on lipolysis and ketogenesis. Memon, R.A., Feingold, K.R., Moser, A.H., Doerrler, W., Grunfeld, C. Endocrinology (1992)
- Regulation of the GTP-binding protein-based antilipolytic system of sheep adipocytes by growth hormone. Doris, R.A., Kilgour, E., Houslay, M.D., Vernon, R.G. J. Endocrinol. (1998)
- Allosteric modulation of adenosine A1 receptor coupling to G-proteins in brain. Childers, S.R., Li, X., Xiao, R., Eisenach, J.C. J. Neurochem. (2005)