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High impact information on Litsea

  • Litsea cubeba oil is an aromatic essential oil extracted from the fresh fruits of Litsea cubeba (Lour.) Pers. It is used as a flavor enhancer in foods, cosmetics, and cigarettes; as a raw material in the manufacture of citral, vitamins A, E, and K, ionone, methyl ionone, and perfumes; and as an antimicrobial and insecticide [1].
  • Natural anti-HIV agents-part I: (+)-demethoxyepiexcelsin and verticillatol from Litsea verticillata [2].
  • The eudesmane sesquiterpenoid, verticillatol (1), as well as the lignan, (+)-5'-demethoxyepiexcelsin (2), and a known lignan, (+)-epiexcelsin (3), were isolated from Litsea verticillata Hance [2].
  • A water-soluble arabinoxylan (D-xylose and L-arabinose in the molar ratio 1.0:3.4) was isolated from the mucilaginous bark of Litsea glutinosa (Lauraceae) [3].
  • Antioxidant activity of Litsea cubeba [4].

Anatomical context of Litsea

  • Both the methanolic extract and its fractions (0.01 mg/ml) from Litsea cubeba bark were found to inhibit NO and PGE2 production in LPS-activated RAW264.7 macrophages without significant cytotoxicity at less than 0.01 mg/ml concentration [5].

Associations of Litsea with chemical compounds


  1. Acute and genetic toxicity of essential oil extracted from Litsea cubeba (Lour.) Pers. Luo, M., Jiang, L.K., Zou, G.L. J. Food Prot. (2005) [Pubmed]
  2. Natural anti-HIV agents-part I: (+)-demethoxyepiexcelsin and verticillatol from Litsea verticillata. Hoang, V.D., Tan, G.T., Zhang, H.J., Tamez, P.A., Hung, N.V., Cuong, N.M., Soejarto, D.D., Fong, H.H., Pezzuto, J.M. Phytochemistry (2002) [Pubmed]
  3. Structural studies of an arabinoxylan isolated from Litsea glutinosa (Lauraceae). Herath, H.M., Kumar, N.S., Wimalasiri, K.M. Carbohydr. Res. (1990) [Pubmed]
  4. Antioxidant activity of Litsea cubeba. Hwang, J.K., Choi, E.M., Lee, J.H. Fitoterapia (2005) [Pubmed]
  5. Effects of methanolic extract and fractions from Litsea cubeba bark on the production of inflammatory mediators in RAW264.7 cells. Choi, E.M., Hwang, J.K. Fitoterapia (2004) [Pubmed]
  6. A new acetylenic ketone from the bark of Litsea rotundifolia var. oblongifolia. Zhao, Y., Song, G.Q., Guo, Y.W. Journal of Asian natural products research. (2005) [Pubmed]
  7. Antibacterial activity of Litsea glutinosa bark. Mandal, S.C., Kumar, C.K., Majumder, A., Majumder, R., Maity, B.C. Fitoterapia (2000) [Pubmed]
  8. Flavonoids from the leaves of Litsea japonica and their anti-complement activity. Lee, S.Y., Min, B.S., Kim, J.H., Lee, J., Kim, T.J., Kim, C.S., Kim, Y.H., Lee, H.K. Phytotherapy research : PTR. (2005) [Pubmed]
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