Chemical Compound Review:
AG-K-31121 3,4-dihydroxy-3- (hydroxymethyl)-6,7...
Synonyms:
NSC-50131, NSC50131, CTK6J9831, HMS3079K12, AC1L68M5, ...
Prasad,
Owen,
Mier,
Giacosa,
Hull,
Spiegelhalder,
Bartsch,
van der Schouw,
Kreijkamp-Kaspers,
Peeters,
Keinan-Boker,
Rimm,
Grobbee,
Linseisen,
Piller,
Hermann,
Chang-Claude,
Hano,
Addi,
Bensaddek,
Crônier,
Baltora-Rosset,
Doussot,
Maury,
Mesnard,
Chabbert,
Hawkins,
Lainé,
Lamblin,
Nakanishi,
Inatomi,
Murata,
Shigeta,
Iida,
Inada,
Murata,
Farrera,
Iinuma,
Tanaka,
Tajima,
Oku,
Prasad,
Noguchi,
Ikeda,
Sasaki,
Yamamoto,
Yamori,
Zeleniuch-Jacquotte,
Lundin,
Micheli,
Koenig,
Lenner,
Muti,
Shore,
Johansson,
Krogh,
Lukanova,
Stattin,
Afanasyeva,
Rinaldi,
Arslan,
Kaaks,
Berrino,
Hallmans,
Toniolo,
Adlercreutz,
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- Stereoselective bimolecular phenoxy radical coupling by an auxiliary (dirigent) protein without an active center. Davin, L.B., Wang, H.B., Crowell, A.L., Bedgar, D.L., Martin, D.M., Sarkanen, S., Lewis, N.G. Science (1997)
- Reduction of serum cholesterol and hypercholesterolemic atherosclerosis in rabbits by secoisolariciresinol diglucoside isolated from flaxseed. Prasad, K. Circulation (1999)
- Oxidative aryl-benzyl coupling. A biomimetic entry to podophyllin lignan lactones. Kende, A.S., Liebeskind, L.S., Mills, J.E., Rutledge, P.S., Curran, D.P. J. Am. Chem. Soc. (1977)
- Justicidin A inhibits the transport of tumor necrosis factor-alpha to cell surface in lipopolysaccharide-stimulated RAW 264.7 macrophages. Tsao, L.T., Lin, C.N., Wang, J.P. Mol. Pharmacol. (2004)
- Circulating enterolactone and risk of endometrial cancer. Zeleniuch-Jacquotte, A., Lundin, E., Micheli, A., Koenig, K.L., Lenner, P., Muti, P., Shore, R.E., Johansson, I., Krogh, V., Lukanova, A., Stattin, P., Afanasyeva, Y., Rinaldi, S., Arslan, A.A., Kaaks, R., Berrino, F., Hallmans, G., Toniolo, P., Adlercreutz, H. Int. J. Cancer (2006)
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- Exposure to flaxseed or its lignan component during different developmental stages influences rat mammary gland structures. Tou, J.C., Thompson, L.U. Carcinogenesis (1999)
- Structure--antitubulin activity relationship in steganacin congeners and analogues. Inhibition of tubulin polymerization in vitro by (+/-)-isodeoxypodophyllotoxin. Zavala, F., Guenard, D., Robin, J.P., Brown, E. J. Med. Chem. (1980)
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- Inhibition of lipopolysaccharide-inducible nitric oxide synthase, TNF-alpha and COX-2 expression by sauchinone effects on I-kappaBalpha phosphorylation, C/EBP and AP-1 activation. Lee, A.K., Sung, S.H., Kim, Y.C., Kim, S.G. Br. J. Pharmacol. (2003)
- Flaxseed and its lignan and oil components reduce mammary tumor growth at a late stage of carcinogenesis. Thompson, L.U., Rickard, S.E., Orcheson, L.J., Seidl, M.M. Carcinogenesis (1996)
- Dioxabicyclooctanyl naphthalenenitriles as nonredox 5-lipoxygenase inhibitors: structure-activity relationship study directed toward the improvement of metabolic stability. Delorme, D., Ducharme, Y., Brideau, C., Chan, C.C., Chauret, N., Desmarais, S., Dubé, D., Falgueyret, J.P., Fortin, R., Guay, J., Hamel, P., Jones, T.R., Lépine, C., Li, C., McAuliffe, M., McFarlane, C.S., Nicoll-Griffith, D.A., Riendeau, D., Yergey, J.A., Girard, Y. J. Med. Chem. (1996)
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- Sesamin metabolites induce an endothelial nitric oxide-dependent vasorelaxation through their antioxidative property-independent mechanisms: possible involvement of the metabolites in the antihypertensive effect of sesamin. Nakano, D., Kwak, C.J., Fujii, K., Ikemura, K., Satake, A., Ohkita, M., Takaoka, M., Ono, Y., Nakai, M., Tomimori, N., Kiso, Y., Matsumura, Y. J. Pharmacol. Exp. Ther. (2006)
- Lignans are involved in the antitumor activity of wheat bran in colon cancer SW480 cells. Qu, H., Madl, R.L., Takemoto, D.J., Baybutt, R.C., Wang, W. J. Nutr. (2005)
- Lignans and tamoxifen, alone or in combination, reduce human breast cancer cell adhesion, invasion and migration in vitro. Chen, J., Thompson, L.U. Breast Cancer Res. Treat. (2003)
- Sauchinone, a lignan from Saururus chinensis, suppresses iNOS expression through the inhibition of transactivation activity of RelA of NF-kappaB. Hwang, B.Y., Lee, J.H., Jung, H.S., Kim, K.S., Nam, J.B., Hong, Y.S., Paik, S.G., Lee, J.J. Planta Med. (2003)
- Inhibitory activity of lignan components from the flower buds of Magnoliae fargesii on the expression of cell adhesion molecules. Ahn, K.S., Jung, K.Y., Kim, J.H., Oh, S.R., Lee, H.K. Biol. Pharm. Bull. (2001)
- 1-Arylnaphthalene lignan: a novel scaffold for type 5 phosphodiesterase inhibitor. Ukita, T., Nakamura, Y., Kubo, A., Yamamoto, Y., Takahashi, M., Kotera, J., Ikeo, T. J. Med. Chem. (1999)
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- Differential accumulation of monolignol-derived compounds in elicited flax (Linum usitatissimum) cell suspension cultures. Hano, C., Addi, M., Bensaddek, L., Crônier, D., Baltora-Rosset, S., Doussot, J., Maury, S., Mesnard, F., Chabbert, B., Hawkins, S., Lainé, E., Lamblin, F. Planta (2006)