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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Caroli Disease

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Disease relevance of Caroli Disease


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Chemical compound and disease context of Caroli Disease


Anatomical context of Caroli Disease


Gene context of Caroli Disease

  • These results suggest that the activation of the MEK5-ERK5 cascade plays a pivotal role in the biliary dysgenesis of PCK rats, and also provide insights into the pathogenesis of Caroli's disease with CHF [7].


  1. Human liver regeneration after major hepatic resection. A study of normal liver and livers with chronic hepatitis and cirrhosis. Nagasue, N., Yukaya, H., Ogawa, Y., Kohno, H., Nakamura, T. Ann. Surg. (1987) [Pubmed]
  2. A complete mutation screen of PKHD1 in autosomal-recessive polycystic kidney disease (ARPKD) pedigrees. Rossetti, S., Torra, R., Coto, E., Consugar, M., Kubly, V., Málaga, S., Navarro, M., El-Youssef, M., Torres, V.E., Harris, P.C. Kidney Int. (2003) [Pubmed]
  3. Septic shock after liver transplantation for Caroli's disease: clinical improvement after treatment with C1-esterase inhibitor. Marx, G., Nashan, B., Cobas Meyer, M., Vangerow, B., Schlitt, H.J., Ziesing, S., Leuwer, M., Piepenbrock, S., Rueckoldt, H. Intensive care medicine. (1999) [Pubmed]
  4. An atypical course of Caroli's disease in a renal transplant patient--case report and review of the literature. Abouchacra, S., Toumeh, S., Boobes, Y., Bernieh, B., Gorka, W. Clin. Nephrol. (2004) [Pubmed]
  5. Case report: chenodeoxycholic acid therapy of intrahepatic radiolucent gallstones in a patient with Caroli's syndrome. Kutz, K., Miederer, S.E., Paumgartner, G. Acta hepato-gastroenterologica. (1978) [Pubmed]
  6. Ursodeoxycholic acid treatment of primary hepatolithiasis in Caroli's syndrome. Ros, E., Navarro, S., Bru, C., Gilabert, R., Bianchi, L., Bruguera, M. Lancet (1993) [Pubmed]
  7. Activation of the MEK5/ERK5 cascade is responsible for biliary dysgenesis in a rat model of Caroli's disease. Sato, Y., Harada, K., Kizawa, K., Sanzen, T., Furubo, S., Yasoshima, M., Ozaki, S., Ishibashi, M., Nakanuma, Y. Am. J. Pathol. (2005) [Pubmed]
  8. Autosomal dominant polycystic kidney disease with anticipation and Caroli's disease associated with a PKD1 mutation. Rapid communication. Torra, R., Badenas, C., Darnell, A., Brú, C., Escorsell, A., Estivill, X. Kidney Int. (1997) [Pubmed]
  9. Role of PTC and ERCP in diagnostic imaging of the hepatobiliary tree: Caroli's disease in two siblings. Perisic, V. J. Pediatr. Gastroenterol. Nutr. (1987) [Pubmed]
  10. Budd-Chiari-like syndrome in Caroli's disease. Chaimoff, C., Lurie, B., Gal, R. J. Clin. Gastroenterol. (1986) [Pubmed]
  11. Diagnosis of Caroli's disease by technetium-99m DISIDA cholescintigraphy. Report of three cases. Cabrera, J., Quintero, E., Bruguera, M., Alarcó, R., Lomeña, F., Humbert, P., de las Casas, P., Rodés, J. Clinical nuclear medicine. (1985) [Pubmed]
  12. A patient with the Caroli syndrome and multiple intrahepatic and extrahepatic cholesterol stones. Hazenberg, H.J. The Netherlands journal of medicine. (1981) [Pubmed]
  13. Caroli's disease: functional diagnosis using 99mTc diethyl-iminodiacetic acid (IDA) hepatobiliary scintigraphy. Lai, F.M., Paramsothy, M., Goh, K.L., Boey, C. Singapore medical journal. (1997) [Pubmed]
  14. Case of the day. Case 5. Congenital dilatation of intrahepatic bile ducts (? caroli disease). Pear, B.L. AJR. American journal of roentgenology. (1980) [Pubmed]
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