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MeSH Review:

Sarcoma Viruses, Murine

McCoy, M.S. et al., Lichtman, A.H. et al., Seeburg, P.H. et al., Liteplo, R.G., Shih, T.Y. et al., et al.

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High impact information on Sarcoma Viruses, Murine

However, Abelson murine leukaemia virus (A-MuLV) infection of murine bone marrow cells in vitro yields mostly immature B-cell lines, and infection of murine bone marrow cells with murine sarcoma viruses carrying ras related genes produces only immature lymphoid cell lines [1].
These activated genes, usually assayed by their ability to induce the malignant transformation of NIH 3T3 cells, are frequently related to the ras oncogene of Harvey (Ha-ras) or Kirsten (Ki-ras) murine sarcoma viruses, or a third member of this family (N-ras) [2].
We identify this tumour oncogene with c-Ki-ras2, one of two known members of the Kirsten ras family of human proto-oncogenes, extending a series of recent reports which have demonstrated homologies between human oncogenes and those of Harvey and Kirsten murine sarcoma viruses [3].
Harvey and Kirsten murine sarcoma viruses each encode a structurally and functionally related 21-kilodalton protein (p21), which is the transforming protein of each virus [4].
Guanine nucleotide-binding activity as an assay for src protein of rat-derived murine sarcoma viruses [5].

Chemical compound and disease context of Sarcoma Viruses, Murine

This report demonstrates that gag-mos fusion proteins from variant strains of murine sarcoma viruses incorporate both myristate and palmitate [6].
Rodent fibroblasts transformed with the Kirsten and Moloney murine sarcoma viruses exhibit increased resistance to the growth inhibitory and cytotoxic action of the carboxylic Na+/H+ ionophore, monensin [7].

Biological context of Sarcoma Viruses, Murine

Characterization of the phosphorylation sites and the surrounding amino acid sequences of the p21 transforming proteins coded for by the Harvey and Kirsten strains of murine sarcoma viruses [8].
Guanine nucleotide binding activity of the src gene product of rat-derived murine sarcoma viruses [9].

Anatomical context of Sarcoma Viruses, Murine

Myeloid cell transformation by ras-containing murine sarcoma viruses [10].

Gene context of Sarcoma Viruses, Murine

The skin fibroblasts from many FPC patients exhibited increased susceptibility to transformation by murine sarcoma viruses [11].
The compound II markedly inhibited the growth of murine sarcoma viruses (MSV) [12].

References

Mature murine B lymphocytes immortalized by Kirsten sarcoma virus. Lichtman, A.H., Reynolds, D.S., Faller, D.V., Abbas, A.K. Nature (1986) [Pubmed]
Biological properties of human c-Ha-ras1 genes mutated at codon 12. Seeburg, P.H., Colby, W.W., Capon, D.J., Goeddel, D.V., Levinson, A.D. Nature (1984) [Pubmed]
Characterization of a human colon/lung carcinoma oncogene. McCoy, M.S., Toole, J.J., Cunningham, J.M., Chang, E.H., Lowy, D.R., Weinberg, R.A. Nature (1983) [Pubmed]
Human genome contains four genes homologous to transforming genes of Harvey and Kirsten murine sarcoma viruses. Chang, E.H., Gonda, M.A., Ellis, R.W., Scolnick, E.M., Lowy, D.R. Proc. Natl. Acad. Sci. U.S.A. (1982) [Pubmed]
Guanine nucleotide-binding activity as an assay for src protein of rat-derived murine sarcoma viruses. Scolnick, E.M., Papageorge, A.G., Shih, T.Y. Proc. Natl. Acad. Sci. U.S.A. (1979) [Pubmed]
Incorporation of lipids into variants of Moloney sarcoma virus which produce gag-mos fusion proteins. Gallick, G.E., Arlinghaus, R.B. Virology (1984) [Pubmed]
Transformed rodent cells exhibit increased resistance to the carboxylic ionophores monensin and nigericin. Liteplo, R.G. Biochem. Biophys. Res. Commun. (1991) [Pubmed]
Characterization of the phosphorylation sites and the surrounding amino acid sequences of the p21 transforming proteins coded for by the Harvey and Kirsten strains of murine sarcoma viruses. Shih, T.Y., Stokes, P.E., Smythers, G.W., Dhar, R., Oroszlan, S. J. Biol. Chem. (1982) [Pubmed]
Guanine nucleotide binding activity of the src gene product of rat-derived murine sarcoma viruses. Scolnick, E.M., Shih, T.Y., Maryak, J., Ellis, R., Chang, E., Lowy, D. Ann. N. Y. Acad. Sci. (1980) [Pubmed]
Myeloid cell transformation by ras-containing murine sarcoma viruses. Pierce, J.H., Aaronson, S.A. Mol. Cell. Biol. (1985) [Pubmed]
Chemical and viral transformation of cultured skin fibroblasts from patients with familial polyposis coli. Miyaki, M., Akamatsu, N., Sato, C., Utsunomiya, J. Mutat. Res. (1988) [Pubmed]
Synthesis and biological investigations of new tuftsin analogs with elongated peptide chain. Konopinska, D., Luczak, M., Gumułka, S. Int. J. Pept. Protein Res. (1983) [Pubmed]

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