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MeSH Review


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Disease relevance of Deafness


Psychiatry related information on Deafness


High impact information on Deafness


Chemical compound and disease context of Deafness


Gene context of Deafness

  • The MAPK/JNK signalling pathway offers potential therapeutic targets for the prevention of acquired deafness [11].
  • Band keratopathy with bilateral deafness as a presenting sign of hyperparathyroidism [12].
  • A 9-year-old girl had congenital deaf-mutism, high-arched palate, complete heterochromia iridis with pigment mottling in the posterior pole of the eye with the hypochromic iris, dyspigmented frontal scalp hair, a history of vitiligo, but with no dystopia canthorum [13].


  1. A novel mutation in the potassium channel gene KVLQT1 causes the Jervell and Lange-Nielsen cardioauditory syndrome. Neyroud, N., Tesson, F., Denjoy, I., Leibovici, M., Donger, C., Barhanin, J., Fauré, S., Gary, F., Coumel, P., Petit, C., Schwartz, K., Guicheney, P. Nat. Genet. (1997) [Pubmed]
  2. Targeted disruption of the Kcnq1 gene produces a mouse model of Jervell and Lange-Nielsen Syndrome. Casimiro, M.C., Knollmann, B.C., Ebert, S.N., Vary, J.C., Greene, A.E., Franz, M.R., Grinberg, A., Huang, S.P., Pfeifer, K. Proc. Natl. Acad. Sci. U.S.A. (2001) [Pubmed]
  3. Acute onset deafness in a 4-year-old girl after a single infusion of cis-platinum. Bührer, C., Weinel, P., Sauter, S., Reiter, A., Riehm, H., Laszig, R. Pediatric hematology and oncology. (1990) [Pubmed]
  4. Incidence of genetic factors in the causation of deafness in childhood. Lenzi, A., Zaghis, A. Scandinavian audiology. Supplementum. (1988) [Pubmed]
  5. Mutation identification in a 5-generation pedigree with autosomal dominant retinitis pigmentosa. Teng, Y., Tian, H., Wang, H., Hu, X., Wang, W., Chen, Y., Yang, Z. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. (2003) [Pubmed]
  6. Ataxia, deafness, leukodystrophy: inherited disorder of the white matter in three related patients. Leuzzi, V., Rinna, A., Gallucci, M., Di Capua, M., Dionisi-Vici, C., Longo, D., Bertini, E. Neurology (2000) [Pubmed]
  7. Hypertrophic cardiomyopathy associated with congenital deaf-mutism. Csanády, M., Högye, M., Forster, T. Eur. Heart J. (1987) [Pubmed]
  8. Bilateral deafness as a prodromal symptom of basilar artery occlusion. Toyoda, K., Hirano, T., Kumai, Y., Fujii, K., Kiritoshi, S., Ibayashi, S. J. Neurol. Sci. (2002) [Pubmed]
  9. Toxic effects of cisplatin alone and in combination with gentamicin in stria vascularis of guinea pigs. Kohn, S., Fradis, M., Podoshin, L., Ben David, Y., Zidan, J., Robinson, E., Nir, I. Laryngoscope (1991) [Pubmed]
  10. Use of an amytal interview in the management of factitious deaf mutism. Marriage, K., Govorchin, M., George, P., Dilworth, C. The Australian and New Zealand journal of psychiatry. (1988) [Pubmed]
  11. The MAPK/JNK signalling pathway offers potential therapeutic targets for the prevention of acquired deafness. Zine, A., van de Water, T.R. Current drug targets. CNS and neurological disorders. (2004) [Pubmed]
  12. Band keratopathy with bilateral deafness as a presenting sign of hyperparathyroidism. Petrohelos, M., Ticoulis, D., Diamantacos, P. The British journal of ophthalmology. (1977) [Pubmed]
  13. Waardenburg's syndrome: case reports in two Nigerians. Amoni, S.S., Abdurrahman, M.B. Journal of pediatric ophthalmology and strabismus. (1979) [Pubmed]
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