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MeSH Review:

Sea Anemones

Nothacker, H.P. et al., Nothacker, H.P. et al., McFarlane, I.D. et al., Carstensen, K. et al., Möller, C. et al., et al.

Heffernan, Winston,

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High impact information on Sea Anemones

Immunocytochemical staining with antiserum against Arg-Asn-NH2 showed that L-3-phenyllactyl-Leu-Arg-Asn-NH2 (Antho-RNamide) was localized in neurons of sea anemones [1].
Isolation of pyroGlu-Gly-Arg-Phe-NH2 (Antho-RFamide), a neuropeptide from sea anemones [2].
Venomous predatory animals, such as snakes, spiders, scorpions, sea anemones, and cone snails, produce a variety of highly stable cystine-constrained peptide scaffolds as part of their neurochemical strategy for capturing prey [3].
The expansion behaviour of sea anemones may be coordinated by two inhibitory neuropeptides, Antho-KAamide and Antho-RIamide [4].
Isolation of less than Glu-Gly-Leu-Arg-Trp-NH2 (Antho-RWamide II), a novel neuropeptide from sea anemones [5].

Biological context of Sea Anemones

Using oligonucleotide probes derived from consensus sequences of known vertebrate and invertebrate G protein-coupled receptors, we have cloned the cDNA for a presumed G protein-coupled receptor from sea anemones [6].

Anatomical context of Sea Anemones

Therefore, we hypothesize that nerve cells that release Antho-KAamide and Antho-RIamide are involved in the expansion phase of feeding behaviour in sea anemones [4].
In the tentacles of certain sea anemones, the primary chemoreceptors bind N-acetylated sugars, such as N-acetylneuraminic acid (NANA) [7].

Associations of Sea Anemones with chemical compounds

Application of low concentrations of Antho-RPamide to tentacle preparations of sea anemones strongly increased the frequency and duration of spontaneous contractions, suggesting that this peptide is involved in neurotransmission [8].
Isolation of less than Glu-Ser-Leu-Arg-Trp-NH2, a novel neuropeptide from sea anemones [9].
All this is strong evidence that the putative glycoprotein hormone receptor from sea anemones is evolutionarily related to those from mammals [6].
Antho-RIamide I is the second neuropeptide from sea anemones that bears the unusual, amino-terminal L-3-phenyllactyl blocking group [10].
Application of low concentrations (10(-8) M) of Antho-RIamide I inhibited spontaneous contractions in several muscle groups of sea anemones, whereas Antho-RIamide II was inactive [10].

Gene context of Sea Anemones

Further, the 490-nm peak (which interferes with quantification of CYP in sea anemones) was greater in the outer region [11].
NADPH-dependent cytochrome c (P450) reductase of the sea anemones was 1.8-3.9 nmol/min/mg protein, which is at the lower end of the range observed in invertebrates [12].
We describe the cloning and analysis of genomic and cDNA copies of a gene from sea anemones that encodes a new member of the G-protein-coupled receptor family [13].
Molecular cloning of a novel, putative G protein-coupled receptor from sea anemones structurally related to members of the FSH, TSH, LH/CG receptor family from mammals [6].
Hemolysins and proteinase inhibitors from sea anemones of the Gulf of Aqaba [14].

Analytical, diagnostic and therapeutic context of Sea Anemones

Molecular cloning of a novel, putative G protein-coupled receptor from sea anemones structurally related to members of the FSH, TSH, LH/CG receptor family from mammals [15].

References

Isolation of L-3-phenyllactyl-Leu-Arg-Asn-NH2 (Antho-RNamide), a sea anemone neuropeptide containing an unusual amino-terminal blocking group. Grimmelikhuijzen, C.J., Rinehart, K.L., Jacob, E., Graff, D., Reinscheid, R.K., Nothacker, H.P., Staley, A.L. Proc. Natl. Acad. Sci. U.S.A. (1990) [Pubmed]
Isolation of pyroGlu-Gly-Arg-Phe-NH2 (Antho-RFamide), a neuropeptide from sea anemones. Grimmelikhuijzen, C.J., Graff, D. Proc. Natl. Acad. Sci. U.S.A. (1986) [Pubmed]
A novel conotoxin framework with a helix-loop-helix (Cs alpha/alpha) fold. Möller, C., Rahmankhah, S., Lauer-Fields, J., Bubis, J., Fields, G.B., Marí, F. Biochemistry (2005) [Pubmed]
The expansion behaviour of sea anemones may be coordinated by two inhibitory neuropeptides, Antho-KAamide and Antho-RIamide. McFarlane, I.D., Hudman, D., Nothacker, H.P., Grimmelikhuijzen, C.J. Proc. Biol. Sci. (1993) [Pubmed]
Isolation of less than Glu-Gly-Leu-Arg-Trp-NH2 (Antho-RWamide II), a novel neuropeptide from sea anemones. Graff, D., Grimmelikhuijzen, C.J. FEBS Lett. (1988) [Pubmed]
Molecular cloning of a novel, putative G protein-coupled receptor from sea anemones structurally related to members of the FSH, TSH, LH/CG receptor family from mammals. Nothacker, H.P., Grimmelikhuijzen, C.J. Biochem. Biophys. Res. Commun. (1993) [Pubmed]
N-acetylneuraminic acid (NANA) stimulates in situ cyclic AMP production in tentacles of sea anemone (Aiptasia pallida): possible role in chemosensitization of nematocyst discharge. Ozacmak, V.H., Thorington, G.U., Fletcher, W.H., Hessinger, D.A. J. Exp. Biol. (2001) [Pubmed]
Isolation of Leu-Pro-Pro-Gly-Pro-Leu-Pro-Arg-Pro-NH2 (Antho-RPamide), an N-terminally protected, biologically active neuropeptide from sea anemones. Carstensen, K., Rinehart, K.L., McFarlane, I.D., Grimmelikhuijzen, C.J. Peptides (1992) [Pubmed]
Isolation of less than Glu-Ser-Leu-Arg-Trp-NH2, a novel neuropeptide from sea anemones. Graff, D., Grimmelikhuijzen, C.J. Brain Res. (1988) [Pubmed]
Isolation of two novel neuropeptides from sea anemones: the unusual, biologically active L-3-phenyllactyl-Tyr-Arg-Ile-NH2 and its des-phenyllactyl fragment Tyr-Arg-Ile-NH2. Nothacker, H.P., Rinehart, K.L., McFarlane, I.D., Grimmelikhuijzen, C.J. Peptides (1991) [Pubmed]
Distribution of microsomal CO-binding chromophores and EROD activity in sea anemone tissues. Heffernan, L.M., Winston, G.W. Mar. Environ. Res. (2000) [Pubmed]
Spectral analysis and catalytic activities of the microsomal mixed-function oxidase system of the sea anemone (phylum: Cnidaria). Heffernan, L.M., Winston, G.W. Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. (1998) [Pubmed]
Cloning of a novel G-protein-coupled receptor from the sea anemone nervous system. New, D.C., Wong, Y.H., Wong, J.T. Biochem. Biophys. Res. Commun. (2000) [Pubmed]
Hemolysins and proteinase inhibitors from sea anemones of the Gulf of Aqaba. Mebs, D., Liebrich, M., Reul, A., Samejima, Y. Toxicon (1983) [Pubmed]
Molecular cloning of a novel, putative G protein-coupled receptor from sea anemones structurally related to members of the FSH, TSH, LH/CG receptor family from mammals. Nothacker, H.P., Grimmelikhuijzen, C.J. Biochem. Biophys. Res. Commun. (1994) [Pubmed]

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