Disease relevance of Lice Infestations

• Although lindane per si is moderately toxic, capable of inducing neurotoxic and hemotoxic effects, there is little evidence that the preparations used in the treatment of scabies and pediculosis give rise to toxic symptoms when applied according to directions [1].
• A case of lindane toxicity in a 24-year-old woman who used lindane shampoo for treatment of an alleged case of lice infestation is described [2].
• Trimethoprim-sulfamethoxazole in the treatment of malaria, toxoplasmosis, and pediculosis [3].

High impact information on Lice Infestations

• Permethrin 1%, lindane 1%, or pyrethrins with piperonyl butoxide is recommended for the treatment of pediculosis pubis [4].
• Lindane 1%, permethrin 1%, and pyrethrins with piperonyl butoxide are all effective treatments for pediculosis [4].
• Single application of Nix (permethrin 1% creme rinse) and Rid were compared as treatments for Pediculosis capitis in 435 patients, the majority of whom were children [5].
• You ought to have your head examined: pediculosis capitis redux [6].
• Treatment of pediculosis pubis. Clinical comparison of efficacy and tolerance of 1% lindane shampoo vs 1% permethrin creme rinse [7].

Chemical compound and disease context of Lice Infestations

• Sea lice infestations on farmed Atlantic salmon in Scotland and the use of ectoparasitic treatments [8].
• Field trial of cypermethrin against lice infestations in goats [9].
• A clinical field trial was performed to evaluate the efficacy of imidacloprid, the active ingredient of Advantage 10% Spot-On, against natural lice infestations on dogs [10].
• On the efficacy of Co-trimoxazole as an oral treatment for pediculosis capitis infestation [11].
• Albendazole: Single or Combination Therapy with Permethrin against Pediculosis Capitis [12].

Biological context of Lice Infestations

• Epidemiology of lindane exposures for pediculosis reported to Poison Centers in Texas, 1998-2002 [13].

References