Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Friedman, S.R. et al.

Friedman, Flom, Kottiri, Zenilman, Curtis, Neaigus, Sandoval, Quinn, Des Jarlais,

Drug use patterns and infection with sexually transmissible agents among young adults in a high-risk neighbourhood in New York City.

AIMS: To determine relationships between drug use "hardness" (defined in increasing order of hardness as no drug use, marijuana use, non-injected heroin or cocaine use, crack smoking and injection drug use) and prevalences of several sexually transmissible infections among young adults in a high-risk neighbourhood. Drug users, particularly injection drug users and crack smokers, may be a core group for some sexually transmitted infections. DESIGN: Cross-sectional survey and assays of young adults from (a) a household probability sample and (b) a targeted sample of youth who have used injected drugs, crack, other cocaine or heroin. SETTING: Bushwick, an impoverished New York City minority neighbourhood with major drug markets. PARTICIPANTS: A total of 363 18-24-year-olds from a household probability sample; 165 Bushwick 18-24-year-olds who have used injected drugs, crack, other cocaine or heroin. MEASUREMENTS: Drug use by self-report; serum- and urine-based assays for HIV, hepatitis B and C, syphilis, gonorrhoea, chlamydia and herpes simplex (type 2). FINDINGS: Household-sample prevalences: HIV, hepatitis C and syphilis, 1%; gonorrhoea 3%; chlamydia 5%; past or present hepatitis B infection 8%; herpes simplex (type 2) 18%. In combined household and targeted samples, hepatitis C and HIV were concentrated among drug injectors. Herpes simplex (type 2), syphilis and hepatitis B increased among women with "hardest drug ever used". CONCLUSIONS: Using "harder" drugs is associated with some but not all of these infections. Prevention efforts should help youth avoid unsafe sex and higher-risk drugs.[1]

References

Drug use patterns and infection with sexually transmissible agents among young adults in a high-risk neighbourhood in New York City. Friedman, S.R., Flom, P.L., Kottiri, B.J., Zenilman, J., Curtis, R., Neaigus, A., Sandoval, M., Quinn, T., Des Jarlais, D.C. Addiction (2003) [Pubmed]

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