- Reduced expression of Hugl-1, the human homologue of Drosophila tumour suppressor gene lgl, contributes to progression of colorectal cancer. Schimanski, C.C., Schmitz, G., Kashyap, A., Bosserhoff, A.K., Bataille, F., Schäfer, S.C., Lehr, H.A., Berger, M.R., Galle, P.R., Strand, S., Strand, D. Oncogene (2005)